| Literature DB >> 16961646 |
L-X Zhu1, Z-W Zhang, C Wang, H-W Yang, Q Zhang, J Cheng.
Abstract
Methicillin susceptibility of 415 staphylococcal isolates from Chinese hospitals was assessed using the CLSI disk-diffusion method with a cefoxitin 30-microg disk in comparison with an oxacillin 1-microg disk. PCR-based detection of mecA was the reference standard. The cefoxitin 30-microg disk performed with almost the same high level of accuracy as the oxacillin 1-microg disk in detecting methicillin resistance in Staphylococcus aureus. For coagulase-negative staphylococci (CoNS), the sensitivity of the cefoxitin 30-microg disk was 90.5%, compared with 83.4% for the oxacillin 1-microg disk. Confirmatory testing of isolates with borderline susceptibility and revision of the cefoxitin breakpoint are proposed in order to categorise CoNS more accurately.Entities:
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Year: 2006 PMID： 16961646 DOI： 10.1111/j.1469-0691.2006.01522.x
Source DB: PubMed Journal: Clin Microbiol Infect ISSN： 1198-743X Impact factor: 8.067