Literature DB >> 16960904

Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry.

Lutz F Tietze1, Birgit Krewer, Holm Frauendorf, Felix Major, Ingrid Schuberth.   

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Year:  2006        PMID: 16960904     DOI: 10.1002/anie.200600935

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  5 in total

1.  Tandem mass spectrometry-based detection of c4'-oxidized abasic sites at specific positions in DNA fragments.

Authors:  Goutam Chowdhury; F Peter Guengerich
Journal:  Chem Res Toxicol       Date:  2009-07       Impact factor: 3.739

2.  Investigation of the transformations of a novel anti-cancer agent combining HPLC, HPLC-MS and direct ESI-HRMS analyses.

Authors:  Lutz F Tietze; Birgit Krewer; Holm Frauendorf
Journal:  Anal Bioanal Chem       Date:  2009-07-31       Impact factor: 4.142

3.  Determination of the biological activity and structure activity relationships of drugs based on the highly cytotoxic duocarmycins and CC-1065.

Authors:  Lutz F Tietze; Birgit Krewer; J Marian von Hof; Holm Frauendorf; Ingrid Schuberth
Journal:  Toxins (Basel)       Date:  2009-12-02       Impact factor: 4.546

4.  Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug mono-therapy of cancer.

Authors:  Lutz F Tietze; Olaf Panknin; Birgit Krewer; Felix Major; Ingrid Schuberth
Journal:  Int J Mol Sci       Date:  2008-05-20       Impact factor: 6.208

5.  Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA.

Authors:  Ansgar Fitzner; Holm Frauendorf; Hartmut Laatsch; Ulf Diederichsen
Journal:  Anal Bioanal Chem       Date:  2008-01-22       Impact factor: 4.142

  5 in total

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