| Literature DB >> 1696060 |
P F Maness1, C G Shores, M Ignelzi.
Abstract
The protooncogene c-src is implicated in the development of the vertebrate nervous system. Its product pp60c-src is a tyrosine-specific protein kinase that is expressed in two phases of neural development. An activated form of the pp60c-src is highly enriched in the membrane of nerve growth cones and in the proximal neuritic shaft of differentiating neurons, as shown in brain and retina. A possible role for pp60c-src in neuronal process extension is suggested that may involve cell-substratum adhesion or motility.Entities:
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Year: 1990 PMID： 1696060 DOI： 10.1007/978-1-4757-5876-4_10
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622