Literature DB >> 16958730

Effect of the association of nystatin with a tissue conditioner on its ultimate tensile strength.

Vanessa Migliorini Urban1, Raphael Freitas de Souza, Cesar Augusto Galvao Arrais, Karina Tostes Borsato, Luís Geraldo Vaz.   

Abstract

PURPOSE: This study evaluated the ultimate tensile strength of a tissue conditioner without nystatin incorporation (GI-control group) and the same tissue conditioner modified by the addition of nystatin in two concentrations: GII-500,000 International Units (U) and GIII-1,000,000 U, in which each milligram of the medicament corresponded to 6079 U.
MATERIALS AND METHODS: Dumbbell-shaped specimens (N= 7) with a central cross-sectional area of 33 x 6 x 3 mm were produced for the three experimental groups. After polymerization following manufacturer's instructions, specimens were immersed in distilled water at 37 degrees C for either 24 hours or 7 days and then tested in tension in the MTS 810 at 40 mm/minute. Data were analyzed by two-way ANOVA followed by Tukey's test, at 95% level of confidence.
RESULTS: The means (force-grams (gf) +/- standard deviation) of the ultimate tensile strength were: GI-634.29 +/- 122.80; GII-561.92 +/- 133.56; and GIII-547.30 +/- 73.47 for 24-hour storage, and GI-536.68 +/- 54.71; GII-467.50 +/- 143.51; and GIII-500.62 +/- 159.76 for 7-day storage. There were no statistically significant differences among the three experimental groups (p > 0.05). The ultimate tensile strength means of all experimental groups after 7 days were significantly lower than those observed after 24 hours (p= 0.04).
CONCLUSIONS: The results of this study suggest that the addition of nystatin into the tissue conditioner investigated in concentrations below 1,000,000 U did not affect its ultimate tensile strength. Copyright (c) 2006 by The American College of Prosthodontists

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Year:  2006        PMID: 16958730     DOI: 10.1111/j.1532-849X.2006.00130.x

Source DB:  PubMed          Journal:  J Prosthodont        ISSN: 1059-941X            Impact factor:   2.752


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