AIM: The aims of the study are to investigate the bactericidal effect of three antiseptics (chlorhexidine solution, povidone-iodine solution, and Walkhoff solution) and to determine the minimum inhibitory concentration and their effect on different microbial species. METHODS AND MATERIALS: The study was performed on microflora derived from root canals with simple and complicated pulp gangrene and on pure strains of Enterococcus and Candida albicans. RESULTS: Chlorhexidine and povidone-iodine proved to have antibacterial and antifungal effects if used in the treatment of pulp gangrene and in cases not responding to conventional therapy. CONCLUSION: According to the obtained results, the spectrum of antibacterial agents used in infected canal irrigation can be enlarged to include the agents tested.
AIM: The aims of the study are to investigate the bactericidal effect of three antiseptics (chlorhexidine solution, povidone-iodine solution, and Walkhoff solution) and to determine the minimum inhibitory concentration and their effect on different microbial species. METHODS AND MATERIALS: The study was performed on microflora derived from root canals with simple and complicated pulp gangrene and on pure strains of Enterococcus and Candida albicans. RESULTS:Chlorhexidine and povidone-iodine proved to have antibacterial and antifungal effects if used in the treatment of pulp gangrene and in cases not responding to conventional therapy. CONCLUSION: According to the obtained results, the spectrum of antibacterial agents used in infected canal irrigation can be enlarged to include the agents tested.