Literature DB >> 16957415

Veralipride-induced acute coronary syndrome unmasking a non-secreting pheochromocytoma.

D Montemurro1, G P Rossi.   

Abstract

The administration of veralipride, a centrally acting dopaminergic type 2 (DA2) receptor antagonist, can decrease hot flushes and improve bone density in post-menopausal women (1). Therefore, it entails an alternative to hormone replacement therapy (HRT) in women who have contraindications to estrogen (1). We herein describe the case of a 52-yr-old lady who presented with an acute coronary syndrome shortly after taking veralipride. Based on knowledge that DA2 receptor antagonists trigger catecholamine release (2), a pheochromocytoma was suspected and thereafter diagnosed and excised. Therefore, this is the first case reporting on veralipride unmasking a silent pheochromocytoma.

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Year:  2006        PMID: 16957415     DOI: 10.1007/BF03344166

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN: 0391-4097            Impact factor:   4.256


  5 in total

1.  Adrenal incidentaloma: an overview of hormonal data from the National Italian Study Group.

Authors:  F Mantero; A M Masini; G Opocher; M Giovagnetti; G Arnaldi
Journal:  Horm Res       Date:  1997

2.  Hypertensive crisis in patients with phaeochromocytoma given metoclopramide.

Authors:  E Agabiti-Rosei; C L Alicandria; L Corea
Journal:  Lancet       Date:  1977-03-12       Impact factor: 79.321

3.  Dopamine receptor expression and function in human normal adrenal gland and adrenal tumors.

Authors:  Rosario Pivonello; Diego Ferone; Wouter W de Herder; Ronald R de Krijger; Marlijn Waaijers; Diana M Mooij; Peter M van Koetsveld; Antonina Barreca; Maria Laura del Basso De Caro; Gaetano Lombardi; Annamaria Colao; Steven W J Lamberts; Leo J Hofland
Journal:  J Clin Endocrinol Metab       Date:  2004-09       Impact factor: 5.958

4.  Endogenous dopamine (DA) and DA2 receptors: a mechanism limiting excessive sympathetic-adrenal discharge in humans.

Authors:  M Mannelli; C Pupilli; G Fabbri; R Musante; M L De Feo; F Franchi; G Giusti
Journal:  J Clin Endocrinol Metab       Date:  1988-03       Impact factor: 5.958

5.  Veralipride administered in combination with raloxifene decreases hot flushes and improves bone density in early postmenopausal women.

Authors:  G Morgante; M Farina; A Cianci; A La Marca; F Petraglia; V De Leo
Journal:  Gynecol Endocrinol       Date:  2004-04       Impact factor: 2.260

  5 in total
  2 in total

Review 1.  Actual status of veralipride use.

Authors:  Sebastián Carranza-Lira
Journal:  Clin Interv Aging       Date:  2010-09-07       Impact factor: 4.458

Review 2.  Adverse drug reactions in patients with phaeochromocytoma: incidence, prevention and management.

Authors:  Graeme Eisenhofer; Graham Rivers; Alejandro L Rosas; Zena Quezado; William M Manger; Karel Pacak
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

  2 in total

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