Literature DB >> 16956203

Stereoselective functionalization of the 1'-position of 4'-thionucleosides.

Prashantha Gunaga1, Hea Ok Kim, Hyuk Woo Lee, Dilip K Tosh, Jae-Sang Ryu, Sun Choi, Lak Shin Jeong.   

Abstract

Stereoselective synthesis of novel 1'-alpha-substituted-4'-thionucleosides was achieved starting from D-gulonic acid gamma-lactone via stereoselective nucleophilic substitution.

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Year:  2006        PMID： 16956203     DOI： 10.1021/ol061548z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  S-Ribosylhomocysteine analogs containing a [4-thio]ribose ring.

Authors:  Adam J Sobczak; Christiane Chbib; Stanislaw F Wnuk
Journal:  Carbohydr Res       Date:  2015-07-23       Impact factor: 2.104

2.  Synthesis of 4'-Ethynyl-2'-deoxy-4'-thioribonucleosides and Discovery of a Highly Potent and Less Toxic NRTI.

Authors:  Kazuhiro Haraguchi; Hisashi Shimada; Keiogo Kimura; Genta Akutsu; Hiromichi Tanaka; Hiroshi Abe; Takayuki Hamasaki; Masanori Baba; Elizabeth A Gullen; Ginger E Dutschman; Yung-Chi Cheng; Jan Balzarini
Journal:  ACS Med Chem Lett       Date:  2011-09-08       Impact factor: 4.345

3.  Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists.

Authors:  Lak Shin Jeong; Shantanu Pal; Seung Ah Choe; Won Jun Choi; Kenneth A Jacobson; Zhan-Guo Gao; Athena M Klutz; Xiyan Hou; Hea Ok Kim; Hyuk Woo Lee; Sang Kook Lee; Dilip K Tosh; Hyung Ryong Moon
Journal:  J Med Chem       Date:  2008-09-24       Impact factor: 7.446

4.  Design and synthesis of truncated 4'-thioadenosine derivatives as potent and selective A3 adenosine receptor antagonists.

Authors:  Xiyan Hou; Shantanu Pal; Won Jun Choi; Hea Ok Kim; Amol Tipnis; Kenneth A Jacobson; Lak Shin Jeong
Journal:  Nucleic Acids Symp Ser (Oxf)       Date:  2008
  4 in total

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