| Literature DB >> 16955535 |
Abstract
Papers on cross-over trials that have appeared in the first 25 years of Statistics in Medicine are reviewed. Papers on bioequivalence are also considered. After a brief statistical summary, individual papers are discussed under seven headings: 1. The two-stage analysis of AB/BA trials, 2. Baselines, 3. Binary and categorical data, 4. Survival data, 5. Modelling carry-over, 6. Bioequivalence and 7. Components of variation. Finally, a brief assessment of the importance in this field of Statistics in Medicine is given.Entities:
Mesh:
Year: 2006 PMID: 16955535 DOI: 10.1002/sim.2706
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373