Literature DB >> 1695454

Modulation of histamine release by rat peritoneal mast cells in a superfusion set-up.

M J Post1, C Moekoet, J Wemer, H H van Rooij, A J Porsius.   

Abstract

A new method is presented for studying mediator release in isolated peritoneal cells of the rat. Using a superfusion technique, cells can be maintained in a continuously cleared medium. Cells were stimulated with antigen, compound 48/80 or A23187 to characterize this preparation. In addition, inhibitory effects of theophylline, isoprenaline and cromoglycate on compound 48/80-induced histamine release were studied. We conclude that superfusion is a valid alternative to study mediator release from isolated peritoneal cells.

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Year:  1990        PMID： 1695454     DOI： 10.1007/bf01968991

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  8 in total

1.  Purification of rat peritoneal mast cells: occupation of IgE-receptors by IgE prevents loss of the receptors.

Authors:  S M Coutts; R E Nehring; N U Jariwala
Journal:  J Immunol       Date:  1980-05       Impact factor: 5.422

Review 2.  Auto-modulation of release of pharmacological mediators of immediate (type I) hypersensitivity. A review.

Authors:  M C Holroyde; J F Burka; P Eyre
Journal:  Agents Actions       Date:  1977-10

3.  Release of adenosine from rat lung by antigen and compound 48/80.

Authors:  B B Fredholm
Journal:  Acta Physiol Scand       Date:  1981-04

4.  Anti-allergic effects of milrinone and sulmazole in isolated rat lungs in comparison with theophylline.

Authors:  M J Post; J D te Biesebeek; H H van Rooij; J Wemer; A J Porsius
Journal:  Int Arch Allergy Appl Immunol       Date:  1989

5.  Differential release of histamine and 5-hydroxytryptamine from rat mast cells: the contribution of amine uptake to the apparent pattern of secretion.

Authors:  W M Purcell; T H Hanahoe
Journal:  Agents Actions       Date:  1990-04

6.  Release of prostaglandins, a prostaglandin metabolite, slow-reacting substance and histamine from anaphylactic lungs, and its modification by catecholamines.

Authors:  R Liebig; W Bernauer; B A Peskar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

7.  On the mechanism by which theophylline inhibits histamine release from rat mast cells.

Authors:  A Sydbom; B B Fredholm
Journal:  Acta Physiol Scand       Date:  1982-02

8.  Mast cell histamine release induced by intermediate products of arachidonic acid metabolism.

Authors:  E Masini; B Palmerani; T Bani-Sacchi; E Giannella; R Fantozzi; P F Mannaioni
Journal:  Int Arch Allergy Appl Immunol       Date:  1987
  8 in total

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