Literature DB >> 1695451

A modified radioimmunoassay for the detection of histamine release in vivo and in vitro in man.

E S Assem1, D K Osei.   

Abstract

Histamine (Hi) release in vitro or in vivo in man was measured by variants of a radioimmunoassay (RIA) procedure. Hi released from isolated basophils was converted enzymically to N-tau-methylhistamine (NMH) which was then measured by a very sensitive RIA. This modified RIA was compared with the standard spectrofluorometric assay and was found to have additional advantages in certain applications. RIA of NMH in plasma was found to be of value in acute medical conditions of obscure aetiology.

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Year:  1990        PMID： 1695451     DOI： 10.1007/bf01969063

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  4 in total

1.  Immunoanalysis of histamine through a novel chemical derivatization.

Authors:  A M Morel; M A Delaage
Journal:  J Allergy Clin Immunol       Date:  1988-10       Impact factor: 10.793

2.  Stimulation of histamine-forming capacity by antigen in sensitized human leucocytes.

Authors:  E S Assem; H O Schild; M R Vickers
Journal:  Int Arch Allergy Appl Immunol       Date:  1972

3.  Neurochemical correlates of behavioural responses to frustrative nonreward in the rat: implications for the role of central noradrenergic neurones in behavioural adaptation to stress.

Authors:  S C Stanford; P Salmon
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

4.  Enzymic histamine metabolism in guinea-pig skin and its role in immediate hypersensitivity reactions.

Authors:  S Yamamoto; D Francis; M W Greaves
Journal:  Clin Exp Immunol       Date:  1976-12       Impact factor: 4.330
  4 in total

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