Literature DB >> 16952873

Therapeutic application of long-circulating liposomal glucocorticoids in auto-immune diseases and cancer.

Raymond M Schiffelers1, Manuela Banciu, Josbert M Metselaar, Gert Storm.   

Abstract

Glucorticoids are potent drugs that have a multitude of pharmacological actions both at genomic and non-genomic levels. Many of the diseases in which glucorticoids are routinely administered are featured by angiogenesis and enhanced capillary permeability, permitting targeted delivery using long-circulating drug delivery systems. By encapsulation of glucorticoids in long-circulating liposomes, drug levels at the site of the pathology are markedly higher, increasing and prolonging therapeutic efficacy in models of rheumatoid arthritis, multiple sclerosis, and cancer.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16952873     DOI： 10.1080/08982100600851029

Source DB:  PubMed          Journal:  J Liposome Res        ISSN： 0898-2104            Impact factor:   3.648


  13 in total

1.  Engineering vascularized tissues using natural and synthetic small molecules.

Authors:  Lauren S Sefcik; Caren E Petrie Aronin; Edward A Botchwey
Journal:  Organogenesis       Date:  2008-10       Impact factor: 2.500

2.  Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

Authors:  Anita Gianella; Peter A Jarzyna; Venkatesh Mani; Sarayu Ramachandran; Claudia Calcagno; Jun Tang; Benjamin Kann; Wouter J R Dijk; Victor L Thijssen; Arjan W Griffioen; Gert Storm; Zahi A Fayad; Willem J M Mulder
Journal:  ACS Nano       Date:  2011-05-25       Impact factor: 15.881

Review 3.  Biomedical nanomaterials for immunological applications: ongoing research and clinical trials.

Authors:  Vincent Lenders; Xanthippi Koutsoumpou; Ara Sargsian; Bella B Manshian
Journal:  Nanoscale Adv       Date:  2020-08-24

4.  Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue.

Authors:  Manuela Banciu; Josbert M Metselaar; Raymond M Schiffelers; Gert Storm
Journal:  Neoplasia       Date:  2008-02       Impact factor: 5.715

Review 5.  Nanotechnology in medical imaging: probe design and applications.

Authors:  David P Cormode; Torjus Skajaa; Zahi A Fayad; Willem J M Mulder
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-12-04       Impact factor: 8.311

6.  Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse.

Authors:  Paola Aulino; Emanuele Berardi; Veronica M Cardillo; Emanuele Rizzuto; Barbara Perniconi; Carla Ramina; Fabrizio Padula; Enrico P Spugnini; Alfonso Baldi; Fabio Faiola; Sergio Adamo; Dario Coletti
Journal:  BMC Cancer       Date:  2010-07-08       Impact factor: 4.430

7.  Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis.

Authors:  Mark E Lobatto; Zahi A Fayad; Stephane Silvera; Esad Vucic; Claudia Calcagno; Venkatesh Mani; Stephen D Dickson; Klaas Nicolay; Manuela Banciu; Raymond M Schiffelers; Josbert M Metselaar; Louis van Bloois; Hai-Shan Wu; John T Fallon; James H Rudd; Valentin Fuster; Edward A Fisher; Gert Storm; Willem J M Mulder
Journal:  Mol Pharm       Date:  2010-11-08       Impact factor: 4.939

8.  Targeted delivery of nanomedicines.

Authors:  Vinod Kumar Khanna
Journal:  ISRN Pharmacol       Date:  2012-04-10

9.  Investigation into the role of tumor-associated macrophages in the antitumor activity of Doxil.

Authors:  Manuela Banciu; Raymond M Schiffelers; Gert Storm
Journal:  Pharm Res       Date:  2008-06-04       Impact factor: 4.200

Review 10.  Tumour-targeted nanomedicines: principles and practice.

Authors:  T Lammers; W E Hennink; G Storm
Journal:  Br J Cancer       Date:  2008-07-22       Impact factor: 7.640
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.