Literature DB >> 16952342

Synthesis of beta-(1-->6)-linked glucosamine oligosaccharides corresponding to fragments of the bacterial surface polysaccharide poly-N-acetylglucosamine.

Marina L Gening1, Yury E Tsvetkov, Gerald B Pier, Nikolay E Nifantiev.   

Abstract

A series of 3-beta-acetamidopropyl oligo-beta-(1-->6)-glucosamines consisting of 5, 7, 9 and 11 glucosamine residues, and a series of corresponding per-N-acetylated derivatives were synthesized using a convergent blockwise approach. These compounds represent fragments of a bacterial surface polysaccharide produced by numerous bacterial pathogens, including Staphylococcus aureus, and will be used as models for its biochemical and immunological properties.

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Year:  2006        PMID： 16952342     DOI： 10.1016/j.carres.2006.08.010

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  13 in total

1.  Protecting group-free glycoligation by the desulfurative rearrangement of allylic disulfides as a means of assembly of oligosaccharide mimetics.

Authors:  Venkataraman Subramanian; Myriame Moumé-Pymbock; Tianshun Hu; David Crich
Journal:  J Org Chem       Date:  2011-03-23       Impact factor: 4.354

2.  Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.

Authors:  David Skurnik; Michael R Davis; Dennis Benedetti; Katie L Moravec; Colette Cywes-Bentley; Damien Roux; David C Traficante; Rebecca L Walsh; Tomas Maira-Litràn; Sara K Cassidy; Christina R Hermos; Thomas R Martin; Erin L Thakkallapalli; Sara O Vargas; Alexander J McAdam; Tami D Lieberman; Roy Kishony; John J Lipuma; Gerald B Pier; Joanna B Goldberg; Gregory P Priebe
Journal:  J Infect Dis       Date:  2012-03-23       Impact factor: 5.226

3.  NMR and conformational studies of linear and cyclic oligo-(1→6)-β-D-glucosamines.

Authors:  Alexey A Grachev; Alexey G Gerbst; Marina L Gening; Denis V Titov; Olga N Yudina; Yury E Tsvetkov; Alexander S Shashkov; Gerald B Pier; Nikolay E Nifantiev
Journal:  Carbohydr Res       Date:  2011-09-05       Impact factor: 2.104

4.  Synthesis of β-(1→6)-linked N-acetyl-D-glucosamine oligosaccharide substrates and their hydrolysis by Dispersin B.

Authors:  Anikó Fekete; Anikó Borbás; Gyöngyi Gyémánt; Lili Kandra; Erika Fazekas; Narayanan Ramasubbu; Sándor Antus
Journal:  Carbohydr Res       Date:  2011-03-23       Impact factor: 2.104

5.  Identification of Poly-N-acetylglucosamine as a Major Polysaccharide Component of the Bacillus subtilis Biofilm Matrix.

Authors:  Damien Roux; Colette Cywes-Bentley; Yi-Fan Zhang; Stephanie Pons; Melissa Konkol; Daniel B Kearns; Dustin J Little; P Lynne Howell; David Skurnik; Gerald B Pier
Journal:  J Biol Chem       Date:  2015-06-15       Impact factor: 5.157

6.  Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine.

Authors:  Caroline Soliman; Anna K Walduck; Elizabeth Yuriev; Jack S Richards; Colette Cywes-Bentley; Gerald B Pier; Paul A Ramsland
Journal:  J Biol Chem       Date:  2018-02-15       Impact factor: 5.157

7.  Synthesis of five nona-β-(1→6)-d-glucosamines with various patterns of N-acetylation corresponding to the fragments of exopolysaccharide of Staphylococcus aureus.

Authors:  Olga N Yudina; Marina L Gening; Yury E Tsvetkov; Alexey A Grachev; Gerald B Pier; Nikolay E Nifantiev
Journal:  Carbohydr Res       Date:  2011-02-23       Impact factor: 2.104

8.  Synthetic {beta}-(1->6)-linked N-acetylated and nonacetylated oligoglucosamines used to produce conjugate vaccines for bacterial pathogens.

Authors:  Marina L Gening; Tomás Maira-Litrán; Andrea Kropec; David Skurnik; Martha Grout; Yury E Tsvetkov; Nikolay E Nifantiev; Gerald B Pier
Journal:  Infect Immun       Date:  2009-11-30       Impact factor: 3.441

9.  A Poly-N-acetylglucosamine-Shiga toxin broad-spectrum conjugate vaccine for Shiga toxin-producing Escherichia coli.

Authors:  Xi Lu; David Skurnik; Clarissa Pozzi; Damien Roux; Colette Cywes-Bentley; Jennifer M Ritchie; Diana Munera; Marina L Gening; Yury E Tsvetkov; Nikolay E Nifantiev; Matthew K Waldor; Gerald B Pier
Journal:  MBio       Date:  2014-03-25       Impact factor: 7.867

10.  Transcriptome sequencing and analysis of the fast growing shoots of moso bamboo (Phyllostachys edulis).

Authors:  Zhenhua Peng; Chunling Zhang; Ying Zhang; Tao Hu; Shaohua Mu; Xueping Li; Jian Gao
Journal:  PLoS One       Date:  2013-11-07       Impact factor: 3.240
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