Literature DB >> 16952158

Lack of neuropeptide Y attenuates the somatic signs of opiate withdrawal.

Valerie G Olson1, Nicholas B Griner, Carrie L Heusner, Richard D Palmiter.   

Abstract

Recent evidence suggests that neuropeptide Y (NPY) may be involved in the neurobiological responses to drugs of abuse. This study was designed to assess the possible contribution of NPY to opiate withdrawal behaviors. Here we report that mice lacking the NPY gene show normal conditioned place aversion to opiate withdrawal, but show attenuated opiate withdrawal somatic signs.

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Year:  2006        PMID: 16952158     DOI: 10.1002/syn.20328

Source DB:  PubMed          Journal:  Synapse        ISSN: 0887-4476            Impact factor:   2.562


  3 in total

Review 1.  Endogenous opiates and behavior: 2006.

Authors:  Richard J Bodnar
Journal:  Peptides       Date:  2007-09-11       Impact factor: 3.750

2.  Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice.

Authors:  Thomas F Gamage; Bogna M Ignatowska-Jankowska; Pretal P Muldoon; Benjamin F Cravatt; M Imad Damaj; Aron H Lichtman
Journal:  Drug Alcohol Depend       Date:  2014-11-26       Impact factor: 4.492

3.  Skin β-endorphin mediates addiction to UV light.

Authors:  Gillian L Fell; Kathleen C Robinson; Jianren Mao; Clifford J Woolf; David E Fisher
Journal:  Cell       Date:  2014-06-19       Impact factor: 41.582

  3 in total

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