| Literature DB >> 16951668 |
Abstract
Celiac disease is a genetic inflammatory disorder with autoimmune components that is induced by the ingestion of dietary gluten. Refractory sprue and enteropathy-associated T-cell lymphoma are rare but distinctive complications of the disease. Although the importance of the adaptive immune response to gluten has been well established, observations now also point towards a central role for the gluten-induced innate stress response in the pathogenesis of celiac disease and its malignant complications.Entities:
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Year: 2006 PMID: 16951668 DOI: 10.1038/ncpgasthep0582
Source DB: PubMed Journal: Nat Clin Pract Gastroenterol Hepatol ISSN: 1743-4378