| Literature DB >> 16950016 |
Charles J N Lacey1, Catherine M Lowndes, Keerti V Shah.
Abstract
Human Papillomavirus (HPV)-6 and -11 are the causative agents of ano-genital warts (GWs) and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are uncommonly found in malignant lesions. GWs are an extremely prevalent sexually transmitted disease, whereas RRP is a rare disease that can be life threatening and requires multiple surgical procedures. GWs and RRP cause substantial healthcare costs. A quadrivalent HPV-6/11/16/18 vaccine (Merck/SPMSD) has shown essentially 100% protection against GWs in women in early studies. Cost-effectiveness analyses are needed to assess the benefits of the HPV-6/11 virus-like particle (VLP) components of the quadrivalent vaccine in population-based vaccination programmes.Entities:
Mesh：
Year: 2006 PMID： 16950016 DOI： 10.1016/j.vaccine.2006.06.015
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641