| Literature DB >> 16949857 |
Véronique Boudolf1, Dirk Inzé, Lieven De Veylder.
Abstract
Progression through the cell cycle is regulated by cyclin-dependent kinases (CDKs). Plants possess a unique class of CDKs, designated B-type CDKs, but seem to lack a functional CDC25 phosphatase, which is a crucial activator of the onset of mitosis in non-plant species. Based on a striking number of functional parallels between the Arabidopsis thaliana CDKB1;1 and the Drosophila melanogaster CDC25 (string), we hypothesize that the acquisition of B-type CDKs and the disappearance of CDC25 in plants might have been associated; in these coupled events, the CDC25-controlled onset of mitosis might have been evolutionarily replaced by a B-type CDK-dominated pathway, eventually resulting in the loss of the CDC25 gene.Entities:
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Year: 2006 PMID: 16949857 DOI: 10.1016/j.tplants.2006.08.009
Source DB: PubMed Journal: Trends Plant Sci ISSN: 1360-1385 Impact factor: 18.313