| Literature DB >> 1694976 |
L A Basharova1, L A Vetrilé, V A Evseev, E A Gromova, N V Bobkova, L A Plakzhinas, L E Fast.
Abstract
The influence of induction of antibodies to the neuromediator serotonin in the case of active immunization of animals with a conjugate serotonin-protein antigen on the distribution of biogenic amines in the brain and on behavioral responses was investigated in experiments on rats. It was shown that active immunization of rats with a serotonin-protein conjugate leads to a decrease in serotonin, its metabolite 5-hydroxyindole-3-acetic acid, as well as dopamine in certain brain structures. Against a background of induction of antibodies to serotonin, the horizontal motor activity of the animals is decreased.Entities:
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Year: 1990 PMID： 1694976 DOI： 10.1007/bf01268129
Source DB: PubMed Journal: Neurosci Behav Physiol ISSN： 0097-0549