OBJECTIVE: Obese adult pregnant women have increased rates of maternal and neonatal complications. Our objective was to examine adverse obstetric outcomes in overweight adolescent women. STUDY DESIGN: In a retrospective case-control study of 4822 women who were < 19 years old, 3324 appropriate-weight subjects (body mass index, 18.5-24.9 kg/m2) and 1498 overweight subjects (body mass index, > or = 25 kg/m2) were compared. Frequencies and odds ratios for adverse maternal or neonatal events were computed. RESULTS: Compared with appropriate-weight adolescents, primary cesarean delivery (odds ratio, 1.6; 95% CI, 1.4-1.9), failure to progress/cephalopelvic disproportion (odds ratio 1.6; 95% CI, 1.3-1.9), labor induction (odds ratio, 1.4; 95% CI, 1.3-1.7), pregnancy-induced hypertension (odds ratio, 1.8; 95% CI, 1.4-2.3), preeclampsia (odds ratio, 1.7; 95% CI, 1.2-2.4), and gestational diabetes mellitus (odds ratio, 3.0, 95% CI, 1.6-5.4) were significantly more common in overweight adolescents. Significant neonatal findings included an increased incidence of macrosomia (odds ratio, 1.6; 95% CI, 1.2-2.0) and a decreased incidence of low birth weight infants (odds ratio, 0.6; 95% CI, 0.4-0.8) and small for gestational age infants (odds ratio, 0.8; 95% CI, 0.7-1.0). CONCLUSION: Overweight adolescent women are at increased risk for adverse neonatal and perinatal outcomes. With rates of overweight increasing overall, overweight in the gravid adolescent is a pressing perinatal and public health concern.
OBJECTIVE:Obese adult pregnant women have increased rates of maternal and neonatal complications. Our objective was to examine adverse obstetric outcomes in overweight adolescent women. STUDY DESIGN: In a retrospective case-control study of 4822 women who were < 19 years old, 3324 appropriate-weight subjects (body mass index, 18.5-24.9 kg/m2) and 1498 overweight subjects (body mass index, > or = 25 kg/m2) were compared. Frequencies and odds ratios for adverse maternal or neonatal events were computed. RESULTS: Compared with appropriate-weight adolescents, primary cesarean delivery (odds ratio, 1.6; 95% CI, 1.4-1.9), failure to progress/cephalopelvic disproportion (odds ratio 1.6; 95% CI, 1.3-1.9), labor induction (odds ratio, 1.4; 95% CI, 1.3-1.7), pregnancy-induced hypertension (odds ratio, 1.8; 95% CI, 1.4-2.3), preeclampsia (odds ratio, 1.7; 95% CI, 1.2-2.4), and gestational diabetes mellitus (odds ratio, 3.0, 95% CI, 1.6-5.4) were significantly more common in overweight adolescents. Significant neonatal findings included an increased incidence of macrosomia (odds ratio, 1.6; 95% CI, 1.2-2.0) and a decreased incidence of low birth weight infants (odds ratio, 0.6; 95% CI, 0.4-0.8) and small for gestational age infants (odds ratio, 0.8; 95% CI, 0.7-1.0). CONCLUSION: Overweight adolescent women are at increased risk for adverse neonatal and perinatal outcomes. With rates of overweight increasing overall, overweight in the gravid adolescent is a pressing perinatal and public health concern.
Authors: Lisa J Germeroth; Maria T Benno; Rachel P Kolko Conlon; Rebecca L Emery; Yu Cheng; Jennifer Grace; Rachel H Salk; Michele D Levine Journal: Contemp Clin Trials Date: 2019-03-06 Impact factor: 2.226