BACKGROUND: It is not always possible to collect information about health from patients, so information from proxies (relatives and others) is used to aid medical decision-making, but there has been no formal evaluation of the reliability of their reports. The aim of this study was to analyse the reliability and validity of the St. George's Respiratory Questionnaire (SGRQ) answered by proxies and to determine their accuracy as raters. METHODS: Stable symptomatic male COPD patients and relatives living in the same house independently completed the same version of the SGRQ. RESULTS: Forty-six male patients were studied; age 72.1+/-7.3 years, pre-bronchodilator FEV(1) 37.9+/-14.7% predicted, 30.4% on long-term oxygen therapy. Internal consistency (Cronbach's alpha) was over 0.73 for all domains and >0.9 for the total score. Their scores correlated with dyspnoea (r=0.30-0.45) and FEV(1) (r=0.4-0.61). The proxies could distinguish between levels of disease severity, but with a weaker discriminant power compared to patients. Seventy-two per cent of proxies over-reported the degree of the patient's overall health status impairment, especially at mild-moderate scores. Proxies showed weaker correlations at the more severe scores. CONCLUSIONS: The SGRQ was reliable and valid when administered to relatives of male COPD patients; however due to the systematic over-reporting of the level of the patient's health status impairment, caution should be applied whilst trying to use proxies as surrogates for male COPD patients.
BACKGROUND: It is not always possible to collect information about health from patients, so information from proxies (relatives and others) is used to aid medical decision-making, but there has been no formal evaluation of the reliability of their reports. The aim of this study was to analyse the reliability and validity of the St. George's Respiratory Questionnaire (SGRQ) answered by proxies and to determine their accuracy as raters. METHODS: Stable symptomatic male COPDpatients and relatives living in the same house independently completed the same version of the SGRQ. RESULTS: Forty-six male patients were studied; age 72.1+/-7.3 years, pre-bronchodilator FEV(1) 37.9+/-14.7% predicted, 30.4% on long-term oxygen therapy. Internal consistency (Cronbach's alpha) was over 0.73 for all domains and >0.9 for the total score. Their scores correlated with dyspnoea (r=0.30-0.45) and FEV(1) (r=0.4-0.61). The proxies could distinguish between levels of disease severity, but with a weaker discriminant power compared to patients. Seventy-two per cent of proxies over-reported the degree of the patient's overall health status impairment, especially at mild-moderate scores. Proxies showed weaker correlations at the more severe scores. CONCLUSIONS: The SGRQ was reliable and valid when administered to relatives of male COPDpatients; however due to the systematic over-reporting of the level of the patient's health status impairment, caution should be applied whilst trying to use proxies as surrogates for male COPDpatients.
Authors: Nienke Nakken; Daisy Ja Janssen; Monique van Vliet; Geeuwke J de Vries; Giny Al Clappers-Gielen; Arent Jan Michels; Jean Wm Muris; Jan H Vercoulen; Emiel Fm Wouters; Martijn A Spruit Journal: Int J Chron Obstruct Pulmon Dis Date: 2016-12-23