Literature DB >> 16948621

The assessment of kidney function by general practitioners in Australian patients with type 2 diabetes (NEFRON-2).

Merlin C Thomas1, Andrew J Weekes, Olivia J Broadley, Mark E Cooper.   

Abstract

OBJECTIVE: To examine factors influencing the identification of kidney impairment in patients with type 2 diabetes in Australian primary care. DESIGN, SETTING AND PARTICIPANTS: 348 general practitioner investigators were asked to estimate kidney function and its severity in 10-15 consecutively presenting patients with type 2 diabetes (n = 3893). They were then asked, for each patient, whether they routinely estimated kidney function. No instruction was provided on how kidney function should be estimated or categorised. Data were collected between April and September 2005. MAIN OUTCOME MEASURES: Kidney function estimated by the Cockcroft-Gault equation using clinical and laboratory data provided by the GP; estimates of kidney function made by the GP.
RESULTS: In 24% of the patients with type 2 diabetes, their GP routinely estimated kidney function. However, few of these patients had impaired kidney function or risk factors for kidney disease. There was a good statistical correlation between the estimates made by GPs and the data-derived estimates (R2 = 0.72). GPs identified patients with data-derived estimates of kidney function < 60 mL/min in over 83% of cases, with a specificity of 90%. Impaired kidney function was reported by GPs in 34.4% of men and 36.4% of women. These figures were discordant with function categorisation using both GP estimates and data-derived values, overlapping in half of the patients. Despite GPs' ability to assess creatinine clearance, "raw" (unstandardised) serum creatinine levels inappropriately influenced the perception of impairment of kidney function.
CONCLUSION: GPs can accurately assess kidney function, without reporting of estimated glomerular filtration rate (eGFR). However, even in patients at increased risk of chronic kidney disease, routine estimates are seldom made. Our findings underline the value of the recent initiative recommending automatic reporting of eGFR in Australia.

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Year:  2006        PMID: 16948621     DOI: 10.5694/j.1326-5377.2006.tb00556.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  3 in total

1.  Study Protocol--accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR study.

Authors:  Louise J Maple-Brown; Paul D Lawton; Jaquelyne T Hughes; Suresh K Sharma; Graham Rd Jones; Andrew G Ellis; Wendy Hoy; Alan Cass; Richard J Macisaac; Ashim K Sinha; Mark Ab Thomas; Leonard S Piers; Leigh C Ward; Katrina Drabsch; Sianna Panagiotopoulos; Robyn McDermott; Kevin Warr; Sajiv Cherian; Alex Brown; George Jerums; Kerin O'Dea
Journal:  BMC Public Health       Date:  2010-02-19       Impact factor: 3.295

2.  Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (national evaluation of the frequency of renal impairment cO-existing with NIDDM [NEFRON] 11).

Authors:  Merlin C Thomas; Richard J Macisaac; George Jerums; Andrew Weekes; John Moran; Jonathan E Shaw; Robert C Atkins
Journal:  Diabetes Care       Date:  2009-05-26       Impact factor: 19.112

3.  The management of diabetes in indigenous Australians from primary care.

Authors:  Mark Thomas; Andrew J Weekes; Merlin C Thomas
Journal:  BMC Public Health       Date:  2007-10-25       Impact factor: 3.295

  3 in total

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