Literature DB >> 169480

Dopamine- and apomorphine-sensitive adenylate cyclase in homogenates of rabbit retina.

M B Bucher, M Schorderet.   

Abstract

Dopamine (0.5-100 muM) as well as apomorphine (1-100 muM) were found to be potent stimulators of adenylate cyclase in homogenates of rabbit retina. When compared with the dopamine-effect at 10 muM, half-stimulation was also obtained in response to noradrenaline or adrenaline, whereas isoprenaline or phenylephrine were ineffective. Furthermore, the dopamine-induced production of cyclic AMP wab blocked by chloropromazine and haloperidol. These data would suggest the occurrence of a specific "dopamine receptor" in the retina of the rabbit.

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Year:  1975        PMID： 169480     DOI： 10.1007/bf00501818

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  10 in total

1.  IDENTIFICATION AND CELLULAR LOCALIZATION OF THE CATECHOLAMINES IN THE RETINA AND THE CHOROID OF THE RABBIT.

Authors:  J HAEGGENDAL; T MALMFORS
Journal:  Acta Physiol Scand       Date:  1965 May-Jun

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography.

Authors:  R Miller; A Horn; L Iversen; R Pinder
Journal:  Nature       Date:  1974-07-19       Impact factor: 49.962

4.  A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate.

Authors:  B L Brown; J D Albano; R P Ekins; A M Sgherzi
Journal:  Biochem J       Date:  1971-02       Impact factor: 3.857

5.  Apomorphine-induced accumulation of cyclic AMP in isolated retinas of the rabbit.

Authors:  M B Bucher; M Schorderet
Journal:  Biochem Pharmacol       Date:  1974-11-01       Impact factor: 5.858

6.  Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".

Authors:  J W Kebabian; G L Petzold; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1972-08       Impact factor: 11.205

7.  A simple, sensitive method for the assay of adenyl cyclase.

Authors:  G Krishna; B Weiss; B B Brodie
Journal:  J Pharmacol Exp Ther       Date:  1968-10       Impact factor: 4.030

8.  Modification of the Lowry procedure for the analysis of proteolipid protein.

Authors:  M B Lees; S Paxman
Journal:  Anal Biochem       Date:  1972-05       Impact factor: 3.365

9.  Stimulation by dopamine of adenylate cyclase in retinal homogenates and of adenosine-3':5'-cyclic monophosphate formation in intact retina.

Authors:  J H Brown; M H Makman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

10.  Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.

Authors:  Y C Clement-Cormier; J W Kebabian; G L Petzold; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205
  10 in total
  2 in total

1.  The effects of dopamine, piribedil (ET-495) and its metabolite S-584 on retinal adenylate cyclase.

Authors:  M Schorderet
Journal:  Experientia       Date:  1975-11-15

2.  [3H]-dopamine release from the rabbit retina.

Authors:  B Bauer; B Ehinger; L Aberg
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1980
  2 in total

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