Literature DB >> 1694629

CD4+ and CD56+ acute monoblastic leukemia.

T Tauchi1, K Ohyashiki, J H Ohyashiki, Y Kawanishi, Y Kimura, M Saito, S Nakazawa, Y Kawai, K Toyama.   

Abstract

We report here a patient with acute monoblastic leukemia whose leukemia cells had CD4 (T4) and CD56 (NKH-1) antigens, in addition to CD36 (OKM5) antigen. The leukemia cells did not have NK or ADCC activities. They showed no rearrangements of immunoglobulin heavy (IgH) chain and T cell receptor (TCR)-beta chain genes, indicating that the leukemia cells were nonlymphoid. The presence of this case suggests that leukemia cells could be originated from monocytes with NK-associated antigen without IgH or TCR rearrangements.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 1694629     DOI: 10.1002/ajh.2830340315

Source DB:  PubMed          Journal:  Am J Hematol        ISSN: 0361-8609            Impact factor:   10.047


  2 in total

1.  Expounding on the essence of epigenetic and genetic abnormalities in blastic plasmacytoid dendritic cell neoplasms.

Authors:  Lhara Lezama; Robert S Ohgami
Journal:  Haematologica       Date:  2019-04       Impact factor: 9.941

2.  Phenotypic and clinical heterogeneity of CD56-positive acute nonlymphoblastic leukemia.

Authors:  M A Reuss-Borst; B Steinke; H D Waller; H J Bühring; C A Müller
Journal:  Ann Hematol       Date:  1992-02       Impact factor: 3.673

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.