Literature DB >> 16942011

Thrombin receptor (protease activated receptor-1) antagonists as potent antithrombotic agents with strong antiplatelet effects.

Samuel Chackalamannil1.   

Abstract

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Year:  2006        PMID: 16942011     DOI: 10.1021/jm0603670

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  26 in total

1.  Pharmacokinetics and pharmacodynamics of the novel PAR-1 antagonist vorapaxar in patients with end-stage renal disease.

Authors:  Teddy Kosoglou; Walter K Kraft; Bharath Kumar; Paul Statkevich; Fengjuan Xuan; Lei Ma; Lisa K Jennings; James E Schiller; Ronald B Langdon; David L Cutler
Journal:  Eur J Clin Pharmacol       Date:  2012-02-08       Impact factor: 2.953

2.  Mutation-prone points in thrombin receptor.

Authors:  Viroj Wiwanitkit
Journal:  J Thromb Thrombolysis       Date:  2007-12-07       Impact factor: 2.300

Review 3.  PAR-1 inhibitor antiplatelet agents: performance below par?

Authors:  Arun Natarajan; Refai Showkathali; Kare Tang
Journal:  Indian Heart J       Date:  2012-09-12

4.  Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

Authors:  Mariappan V Chelliah; Keith Eagen; Zhuyan Guo; Samuel Chackalamannil; Yan Xia; Hsingan Tsai; William J Greenlee; Ho-Sam Ahn; Stan Kurowski; George Boykow; Yunsheng Hsieh; Madhu Chintala
Journal:  ACS Med Chem Lett       Date:  2014-03-11       Impact factor: 4.345

5.  Discovery of Octahydroindenes as PAR1 Antagonists.

Authors:  Sunkyung Lee; Jong-Hwan Song; Chul Min Park; Jin-Seok Kim; Ji-Hye Jeong; Woo-Young Cho; Dong-Chul Lim
Journal:  ACS Med Chem Lett       Date:  2013-09-10       Impact factor: 4.345

6.  Himbacine-derived thrombin receptor antagonists: c7-aminomethyl and c9a-hydroxy analogues of vorapaxar.

Authors:  Mariappan V Chelliah; Samuel Chackalamannil; Yan Xia; William J Greenlee; Ho-Sam Ahn; Stan Kurowski; George Boykow; Yunsheng Hsieh; Madhu Chintala
Journal:  ACS Med Chem Lett       Date:  2013-12-18       Impact factor: 4.345

Review 7.  Thrombin receptor antagonists for the treatment of atherothrombosis: therapeutic potential of vorapaxar and E-5555.

Authors:  Sergio Leonardi; Pierluigi Tricoci; Richard C Becker
Journal:  Drugs       Date:  2010-10-01       Impact factor: 9.546

Review 8.  Antiplatelet therapy: thrombin receptor antagonists.

Authors:  Antonio Tello-Montoliu; Salvatore D Tomasello; Masafumi Ueno; Dominick J Angiolillo
Journal:  Br J Clin Pharmacol       Date:  2011-10       Impact factor: 4.335

Review 9.  Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?

Authors:  R C Chambers
Journal:  Br J Pharmacol       Date:  2008-01-28       Impact factor: 8.739

Review 10.  Platelet thrombin receptor antagonism and atherothrombosis.

Authors:  Dominick J Angiolillo; Davide Capodanno; Shinya Goto
Journal:  Eur Heart J       Date:  2009-11-30       Impact factor: 29.983

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