Literature DB >> 16941380

Less than 95% adherence to nonnucleoside reverse-transcriptase inhibitor therapy can lead to viral suppression.

David R Bangsberg1.   

Abstract

For antiretroviral therapy, the 95% adherence "threshold" is based on nucloside-exposed patients who are receiving partially suppressive, unboosted protease inhibitor regimens. Using unannounced pill counts and electronic medication monitoring, viral suppression is common with a 54%-100% mean adherence level to nonnucleoside reverse-transcriptase-inhibitor regimens. Although perfect adherence is an important goal, viral suppression is possible with moderate adherence to potent regimens.

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Year:  2006        PMID: 16941380     DOI: 10.1086/507526

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  258 in total

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Authors:  Dean G Cruess; Seth C Kalichman; Christine Amaral; Connie Swetzes; Chauncey Cherry; Moira O Kalichman
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Journal:  Can J Hosp Pharm       Date:  2012-03

4.  Situational temptation for HIV medication adherence in high-risk youth.

Authors:  Karen E Macdonell; Sylvie Naar-King; Debra A Murphy; Jeffrey T Parsons; Heather Huszti
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5.  HIV-infected individuals who use alcohol and other drugs, and virologic suppression.

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6.  Superiority of directly administered antiretroviral therapy over self-administered therapy among HIV-infected drug users: a prospective, randomized, controlled trial.

Authors:  Frederick L Altice; Duncan Smith-Rohrberg Maru; R Douglas Bruce; Sandra A Springer; Gerald H Friedland
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7.  The Association Between Changes in Alcohol Use and Changes in Antiretroviral Therapy Adherence and Viral Suppression Among Women Living with HIV.

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Review 8.  Identification of evidence-based interventions for promoting HIV medication adherence: findings from a systematic review of U.S.-based studies, 1996-2011.

Authors:  Mahnaz R Charania; Khiya J Marshall; Cynthia M Lyles; Nicole Crepaz; Linda S Kay; Linda J Koenig; Paul J Weidle; David W Purcell
Journal:  AIDS Behav       Date:  2014-04

9.  A Randomized Controlled Trial of Rise, a Community-Based Culturally Congruent Adherence Intervention for Black Americans Living with HIV.

Authors:  Laura M Bogart; Matt G Mutchler; Bryce McDavitt; David J Klein; William E Cunningham; Kathy J Goggin; Bonnie Ghosh-Dastidar; Nikki Rachal; Kelsey A Nogg; Glenn J Wagner
Journal:  Ann Behav Med       Date:  2017-12

10.  A Structural Equation Model of HIV-related Symptoms, Depressive Symptoms, and Medication Adherence.

Authors:  Moka Yoo-Jeong; Drenna Waldrop-Valverde; Katryna McCoy; Raymond L Ownby
Journal:  J HIV AIDS       Date:  2016-04-06
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