Literature DB >> 1694094

Cholesterol as a target for toxins.

B de Kruijff1.   

Abstract

A mechanism is proposed for the way in which cholesterol facilitates channel formation by polyene antibiotics and bacterial protein toxins. Central elements of the model are: (i) interactions between the ring system of the sterol and rigid elements of the polyene or toxin molecule, and (ii) the specific orientation of cholesterol within the membrane.

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Year:  1990        PMID： 1694094     DOI： 10.1007/bf01116571

Source DB:  PubMed          Journal:  Biosci Rep        ISSN： 0144-8463            Impact factor:   3.840


  9 in total

1.  Interaction of melittin with membrane cholesterol: a fluorescence approach.

Authors:  H Raghuraman; Amitabha Chattopadhyay
Journal:  Biophys J       Date:  2004-10       Impact factor: 4.033

2.  Characterization of the solution properties and conformation of pneumolysin, the membrane-damaging toxin of Streptococcus pneumoniae.

Authors:  P J Morgan; P G Varley; A J Rowe; P W Andrew; T J Mitchell
Journal:  Biochem J       Date:  1993-12-15       Impact factor: 3.857

3.  A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers.

Authors:  Y E Korchev; C L Bashford; C Pederzolli; C A Pasternak; P J Morgan; P W Andrew; T J Mitchell
Journal:  Biochem J       Date:  1998-02-01       Impact factor: 3.857

4.  Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress.

Authors:  Katrin Kuehnle; Arames Crameri; Roland E Kälin; Paola Luciani; Susanna Benvenuti; Alessandro Peri; Francesca Ratti; Monica Rodolfo; Luka Kulic; Frank L Heppner; Roger M Nitsch; M Hasan Mohajeri
Journal:  Mol Cell Biol       Date:  2007-11-05       Impact factor: 4.272

5.  The interaction of aurein 2.5 with fungal membranes.

Authors:  Sarah R Dennison; Leslie H G Morton; Frederick Harris; David A Phoenix
Journal:  Eur Biophys J       Date:  2014-04-13       Impact factor: 1.733

6.  Reduced sensitivity of Niemann-Pick C1-deficient cells to theta-toxin (perfringolysin O): sequestration of toxin to raft-enriched membrane vesicles.

Authors:  Yuki Ohsaki; Yuko Sugimoto; Michitaka Suzuki; Toshiyuki Kaidoh; Yukiko Shimada; Yoshiko Ohno-Iwashita; Joanna P Davies; Yiannis A Ioannou; Kousaku Ohno; Haruaki Ninomiya
Journal:  Histochem Cell Biol       Date:  2004-04-07       Impact factor: 4.304

7.  Channel Formation and Membrane Deformation via Sterol-Aided Polymorphism of Amphidinol 3.

Authors:  Masayuki Iwamoto; Ayumi Sumino; Eri Shimada; Masanao Kinoshita; Nobuaki Matsumori; Shigetoshi Oiki
Journal:  Sci Rep       Date:  2017-09-07       Impact factor: 4.379

Review 8.  Traditional and Computational Screening of Non-Toxic Peptides and Approaches to Improving Selectivity.

Authors:  Alberto A Robles-Loaiza; Edgar A Pinos-Tamayo; Bruno Mendes; Josselyn A Ortega-Pila; Carolina Proaño-Bolaños; Fabien Plisson; Cátia Teixeira; Paula Gomes; José R Almeida
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-08

9.  A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.

Authors:  K Salzwedel; J T West; E Hunter
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103
  9 in total

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