Literature DB >> 16940126

Activity of picolinic acid in combination with the antiprotozoal drug quinacrine against Mycobacterium avium complex.

Toshiaki Shimizu1, Haruaki Tomioka.   

Abstract

We studied the in vitro and in vivo antimicrobial activities of picolinic acid (PA) in combination with the antiprotozoal drug quinacrine against intramacrophage Mycobacterium avium complex (MAC). Quinacrine significantly potentiated the anti-MAC activity of PA, suggesting the usefulness of this combination in the clinical control of MAC infection.

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Year:  2006        PMID: 16940126      PMCID: PMC1563513          DOI: 10.1128/AAC.01510-05

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  20 in total

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4.  Mefloquine, moxifloxacin, and ethambutol are a triple-drug alternative to macrolide-containing regimens for treatment of Mycobacterium avium disease.

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5.  Macrophage control of mycobacterial growth induced by picolinic acid is dependent on host cell apoptosis.

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6.  [Effect of combined chemotherapy following the guidelines on treatment for Mycobacterium avium complex pulmonary disease].

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7.  Induction of Mycobacterium avium growth restriction and inhibition of phagosome-endosome interactions during macrophage activation and apoptosis induction by picolinic acid plus IFNgamma.

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9.  Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine.

Authors:  Esteban C Nannini; Michael Keating; Peter Binstock; George Samonis; Dimitrios P Kontoyiannis
Journal:  J Infect       Date:  2002-04       Impact factor: 6.072

10.  Characterization and quantitation of a zinc-binding ligand in human milk.

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Journal:  Pediatr Res       Date:  1980-07       Impact factor: 3.756

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  3 in total

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Authors:  R S Grant; S E Coggan; G A Smythe
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Review 2.  Tryptophan Metabolites Along the Microbiota-Gut-Brain Axis: An Interkingdom Communication System Influencing the Gut in Health and Disease.

Authors:  Annalisa Bosi; Davide Banfi; Michela Bistoletti; Cristina Giaroni; Andreina Baj
Journal:  Int J Tryptophan Res       Date:  2020-06-11

3.  Inhibiting Sialidase-Induced TGF-β1 Activation Attenuates Pulmonary Fibrosis in Mice.

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  3 in total

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