Literature DB >> 16936990

[Growth and body composition in children with type 1 diabetes mellitus].

Maria F V M Paulino1, Sofia H V de Lemos-Marini, Gil Guerra-Júnior, Walter José Minicucci, Carolina Taddeo Mendes, André Moreno Morcillo.   

Abstract

OBJECTIVE: To evaluate the growth and body composition of pre-pubertal diabetic children, and to check for influence of the age of diabetes onset and length, sex, insulin requirement and glycosylated hemoglobin. PATIENTS AND METHODS: 59 diabetic children (39 M; 29 F), age 1.2-11.5 years, and 67 controls (36 M; 31 F), age 1.2-11.7 years were included. Weight, height, body mass index (BMI), arm circumference, skin folds, fat mass and muscle areas were evaluated and transformed into standard deviation scores (SDS).
RESULTS: Among the diabetic children the mean height SDS was -0.13 (+/- 0.97) while in the control group it was 0.28 (+/- 0.86) (p= 0.013). The difference between the first and the current height SDS showed that the height SDS decreased significantly (p< 0.001) and multiple regression analysis indicated correlation with the duration of the disease. The mean arm fat SDS also revealed difference (p< 0.001). The means for weight, BMI, addition of 3 skinfolds and muscle mass did not demonstrate difference between the groups.
CONCLUSIONS: The diabetic children showed reduction of height SDS during the period studied and they were significantly shorter than the controls, even though their statures were within the population standards. The arm fat area also showed an increase in relation with the controls.

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Year:  2006        PMID: 16936990     DOI: 10.1590/s0004-27302006000300012

Source DB:  PubMed          Journal:  Arq Bras Endocrinol Metabol        ISSN: 0004-2730


  2 in total

1.  Growth attainments of Indian children with type 1 diabetes: a mixed longitudinal study.

Authors:  Rohan H Ganvir; Anil Kumar Bhalla; Devi Dayal
Journal:  Indian J Pediatr       Date:  2014-05-15       Impact factor: 1.967

2.  Body fat composition and miR-378 expression profiling in patients with type 1 diabetes.

Authors:  Lissette Duarte; Diego F García-Díaz; Francisco Pérez-Bravo
Journal:  Ann Pediatr Endocrinol Metab       Date:  2020-06-30
  2 in total

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