Literature DB >> 16935964

Special problems of children with myalgic encephalomyelitis/chronic fatigue syndrome and the enteroviral link.

J Colby1.   

Abstract

Since 1997, it has been known that myalgic encephalomyelitis/chronic fatigue syndrome constitutes the biggest cause of long-term sickness leading to absence from school, in both staff and pupils. The scale of the problem in children is substantial, and the pattern of illness in schools suggests a prominent role for viral infection--for example, the clustering of cases. The Dowsett-Colby study of 1997, researching long-term sickness, reported on a school roll of 333,024 pupils and 27,327 staff, and found a prevalence of long-term sickness in 70 of 100,000 pupils and 500 of 100,000 staff; 39% of cases were in clusters of three or more. The peak age was 14-16 years. The illness is known to be potentially severe and chronic. In addition, the Tymes Trust has reported that many affected children struggle for recognition of their needs, and are bullied by medical and educational professionals. Children should have time to recover sufficiently before returning to school; sustainable, energy-efficient and often home-based education is important here to fulfil legal obligations. Research is needed on viruses that trigger childhood myalgic encephalomyelitis--for example, enteroviruses--and on the neurocognitive defects caused by myalgic encephalomyelitis. We should recognise the value of previous biological research and records of outbreaks, and I recommend that myalgic encephalomyelitis be made notifiable owing to the encephalitic nature of the effects commonly reported in this illness.

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Year:  2006        PMID: 16935964      PMCID: PMC1860612          DOI: 10.1136/jcp.2006.042606

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  8 in total

Review 1.  The role of enterovirus in chronic fatigue syndrome.

Authors:  J K S Chia
Journal:  J Clin Pathol       Date:  2005-11       Impact factor: 3.411

2.  Myalgic encephalomyelitis--a persistent enteroviral infection?

Authors:  E G Dowsett; A M Ramsay; R A McCartney; E J Bell
Journal:  Postgrad Med J       Date:  1990-07       Impact factor: 2.401

Review 3.  Human enteroviral infections.

Authors:  E G Dowsett
Journal:  J Hosp Infect       Date:  1988-02       Impact factor: 3.926

Review 4.  Pathogenesis of poliovirus infections.

Authors:  R T Johnson
Journal:  Ann N Y Acad Sci       Date:  1995-05-25       Impact factor: 5.691

5.  Spinal fluid abnormalities in patients with chronic fatigue syndrome.

Authors:  Benjamin H Natelson; Shelley A Weaver; Chin-Lin Tseng; John E Ottenweller
Journal:  Clin Diagn Lab Immunol       Date:  2005-01

6.  Patients with chronic fatigue syndrome have reduced absolute cortical blood flow.

Authors:  Kazuhiro Yoshiuchi; Jeffrey Farkas; Benjamin H Natelson
Journal:  Clin Physiol Funct Imaging       Date:  2006-03       Impact factor: 2.273

7.  Increased neutrophil apoptosis in chronic fatigue syndrome.

Authors:  G Kennedy; V Spence; C Underwood; J J F Belch
Journal:  J Clin Pathol       Date:  2004-08       Impact factor: 3.411

Review 8.  Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome.

Authors:  V A Spence; F Khan; G Kennedy; N C Abbot; J J F Belch
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2004-04       Impact factor: 4.006

  8 in total
  1 in total

Review 1.  Myalgic Encephalomyelitis: Symptoms and Biomarkers.

Authors:  Leonard A Jason; Marcie L Zinn; Mark A Zinn
Journal:  Curr Neuropharmacol       Date:  2015       Impact factor: 7.363

  1 in total

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