Literature DB >> 16935516

Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU).

Jan Marik1, Julie L Sutcliffe.   

Abstract

The widely used bifunctional labeling reagent 4-[18F]fluorobenzoic acid ([18F]FBA) and its activated form N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) were prepared using a modified Siemens/CTI chemistry process control unit (CPCU) double vessel [18F]FDG module. The products were obtained with a radiochemical yield greater than 99% with decay corrected yields of 77+/-5% (n=4) for [18F]FBA and 46+/-5% (n=4) for [18F]SFB. The presented synthetic procedure is highly reproducible and fully automated.

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Year:  2006        PMID： 16935516     DOI： 10.1016/j.apradiso.2006.06.007

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  18 in total

1.  Radiohalogenated prostate-specific membrane antigen (PSMA)-based ureas as imaging agents for prostate cancer.

Authors:  Ying Chen; Catherine A Foss; Youngjoo Byun; Sridhar Nimmagadda; Mrudula Pullambhatla; James J Fox; Mark Castanares; Shawn E Lupold; John W Babich; Ronnie C Mease; Martin G Pomper
Journal:  J Med Chem       Date:  2008-12-25       Impact factor: 7.446

2.  High-throughput in vivo screening of targeted molecular imaging agents.

Authors:  M Karen J Gagnon; Sven H Hausner; Jan Marik; Craig K Abbey; John F Marshall; Julie L Sutcliffe
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-07       Impact factor: 11.205

3.  Fully automated preparation and conjugation of N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) with RGD peptide using a GE FASTlab™ synthesizer.

Authors:  David Thonon; David Goblet; Eve Goukens; Geoffroy Kaisin; Jérôme Paris; Joël Aerts; Steve Lignon; Xavier Franci; Roland Hustinx; André Luxen
Journal:  Mol Imaging Biol       Date:  2011-12       Impact factor: 3.488

4.  Microwave-assisted one-pot synthesis of N-succinimidyl-4[ ¹⁸F]fluorobenzoate ([¹⁸F]SFB).

Authors:  Shuang Hou; Duy Linh Phung; Wei-Yu Lin; Ming-wei Wang; Kan Liu; Clifton Kwang-Fu Shen
Journal:  J Vis Exp       Date:  2011-06-28       Impact factor: 1.355

5.  Highlighting the Versatility of the Tracerlab Synthesis Modules. Part 1: Fully Automated Production of [F]Labelled Radiopharmaceuticals using a Tracerlab FX(FN).

Authors:  Xia Shao; Raphaël Hoareau; Brian G Hockley; Louis J M Tluczek; Bradford D Henderson; Henry C Padgett; Peter J H Scott
Journal:  J Labelled Comp Radiopharm       Date:  2011-05-30       Impact factor: 1.921

6.  Copper-Free Click for PET: Rapid 1,3-Dipolar Cycloadditions with a Fluorine-18 Cyclooctyne.

Authors:  Richard D Carpenter; Sven H Hausner; Julie L Sutcliffe
Journal:  ACS Med Chem Lett       Date:  2011-10-07       Impact factor: 4.345

7.  Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models.

Authors:  Brandon Carney; Giuseppe Carlucci; Beatriz Salinas; Valentina Di Gialleonardo; Susanne Kossatz; Axel Vansteene; Valerie A Longo; Alexander Bolaender; Gabriela Chiosis; Kayvan R Keshari; Wolfgang A Weber; Thomas Reiner
Journal:  Mol Imaging Biol       Date:  2016-06       Impact factor: 3.488

8.  In vivo positron emission tomography (PET) imaging with an alphavbeta6 specific peptide radiolabeled using 18F-"click" chemistry: evaluation and comparison with the corresponding 4-[18F]fluorobenzoyl- and 2-[18F]fluoropropionyl-peptides.

Authors:  Sven H Hausner; Jan Marik; M Karen J Gagnon; Julie L Sutcliffe
Journal:  J Med Chem       Date:  2008-09-12       Impact factor: 7.446

9.  Fully automated production of diverse 18F-labeled PET tracers on the ELIXYS multireactor radiosynthesizer without hardware modification.

Authors:  Mark Lazari; Jeffrey Collins; Bin Shen; Mohammed Farhoud; Daniel Yeh; Brandon Maraglia; Frederick T Chin; David A Nathanson; Melissa Moore; R Michael van Dam
Journal:  J Nucl Med Technol       Date:  2014-07-17

10.  Design, synthesis, and preliminary in vitro and in vivo evaluation of N-(2-diethylaminoethyl)-4-[18F]fluorobenzamide ([18F]-DAFBA): a novel potential PET probe to image melanoma tumors.

Authors:  Sudha Garg; Kanchan Kothari; Shankar R Thopate; Aniruddha K Doke; Pradeep K Garg
Journal:  Bioconjug Chem       Date:  2009-03-18       Impact factor: 4.774
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