Literature DB >> 16935274

NMDA receptor antagonist MK-801 infused into the insular cortex prevents the attenuation of gustatory neophobia in rats.

Yazmín Figueroa-Guzmán1, Jeffrey S Kuo, Steve Reilly.   

Abstract

Gustatory neophobia dissipates with repeated exposures to an initially novel taste solution. The aim of the present study was to determine whether NMDA receptors in the insular cortex are involved in this experience-dependent process. Results showed that acute microinfusion of MK-801 into the insular cortex prevented the attenuation of gustatory neophobia indicating that this process is an NMDA receptor-dependent phenomenon.

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Year:  2006        PMID： 16935274     DOI： 10.1016/j.brainres.2006.07.036

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  5 in total

1.  Taste neophobia and c-Fos expression in the rat brain.

Authors:  Jian-You Lin; Chris Roman; Joe Arthurs; Steve Reilly
Journal:  Brain Res       Date:  2012-02-12       Impact factor: 3.252

2.  NMDA receptors in the basolateral amygdala and gustatory neophobia.

Authors:  Yazmín Figueroa-Guzmán; Steve Reilly
Journal:  Brain Res       Date:  2008-03-07       Impact factor: 3.252

3.  Insular cortex lesions fail to block flavor and taste preference learning in rats.

Authors:  Khalid Touzani; Anthony Sclafani
Journal:  Eur J Neurosci       Date:  2007-09-06       Impact factor: 3.386

4.  Taste, olfactory and trigeminal neophobia in rats with forebrain lesions.

Authors:  Jian-You Lin; Christopher Roman; Justin St Andre; Steve Reilly
Journal:  Brain Res       Date:  2008-11-21       Impact factor: 3.252

5.  Molecular mechanisms underlying memory consolidation of taste information in the cortex.

Authors:  Shunit Gal-Ben-Ari; Kobi Rosenblum
Journal:  Front Behav Neurosci       Date:  2012-01-05       Impact factor: 3.558
  5 in total

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