| Literature DB >> 16935207 |
Abstract
VEGF plays a pivotal role in the neovascularization of the choroid in AMD. Anti-VEGF agents have been developed to target VEGF itself or its receptor signal transduction pathway, and have shown promising results in clinical trials. The combination of anti-VEGF strategies with established treatment modalities may have additional efficacy. Safe and effective drug-delivery systems are also required for the successful anti-VEGF therapies for AMD and other ocular diseases with CNV.Entities:
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Year: 2006 PMID： 16935207 DOI： 10.1016/j.ohc.2006.05.001
Source DB: PubMed Journal: Ophthalmol Clin North Am ISSN： 0896-1549