Literature DB >> 16935124

Encouraging results for the Contegra conduit in the problematic right ventricle-to-pulmonary artery connection.

David L S Morales1, Brandi E Braud, Kathryn S Gunter, Kathleen E Carberry, Karol A Arrington, Jeffrey S Heinle, E Dean McKenzie, Charles D Fraser.   

Abstract

OBJECTIVE: The Contegra conduit was developed for right ventricular outflow tract reconstruction. This report evaluates the Contegra conduit, with focus on certain subpopulations in which conduits are known to perform poorly (ie, patients with previous homograft conduits and infants).
METHODS: A retrospective review of 76 patients who had 77 Contegra conduits placed for right ventricular outflow tract reconstruction (January 2001 through August 2005) was completed. Characteristics include the following: median age of 1.6 years (range, 17 days-15.1 years), weight of 9.8 kg (range, 2.5-64.0 kg), and conduit diameter of 16 mm (range, 12-22 mm). Operations performed include right ventricular outflow tract reconstruction for pulmonary atresia-stenosis (n = 33), conduit exchange (n = 28), truncus repair (n = 7), primary conduit placement (n = 6), and the Ross procedure (n = 3). Seventy-nine percent were reoperations.
RESULTS: There was no hospital mortality. Mean follow-up was 20 +/- 14 months. One-, 2-, and 3- year freedom from severe conduit regurgitation was 97%, 86%, and 81%, respectively, and freedom from severe conduit stenosis was 100%. Freedom from reoperation for conduit failure at 1 and 3 years is 98.3% and 93.1%, respectively. All conduit failures (n = 3) were for asymptomatic conduit pseudoaneurysms in the setting of multiple-level pulmonary branch stenoses. Survival at 3 years is 96%. Infants (n = 26) had a freedom from Contegra conduit failure at 3 years of 100%. Patients with previous homograft conduits (n = 26) had a freedom from Contegra conduit failure at 3 years of 100%.
CONCLUSION: At midterm follow-up, the Contegra conduit remains a reliable, accessible, and easily implantable conduit for right ventricular outflow tract reconstruction. It appears to be the most promising conduit option for patients with previous homograft conduits and for infants.

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Year:  2006        PMID: 16935124     DOI: 10.1016/j.jtcvs.2006.03.061

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  7 in total

1.  Early clinical outcomes of right ventricular outflow tract reconstruction with small caliber bovine jugular vein conduit (Contegra®) in small children.

Authors:  Takashi Kido; Takaya Hoashi; Koji Kagisaki; Toshiki Fujiyoshi; Masataka Kitano; Kenichi Kurosaki; Isao Shiraishi; Toshikatsu Yagihara; Yoshiki Sawa; Hajime Ichikawa
Journal:  J Artif Organs       Date:  2016-05-28       Impact factor: 1.731

2.  Mid-term outcomes of Contegra implantation for the reconstruction of the right ventricular outflow tract to proximal branch pulmonary arteries: Japan multicentre study.

Authors:  Takaya Hoashi; Hajime Ichikawa; Keiichi Hirose; Naohiro Horio; Takahisa Sakurai; Hironori Matsuhisa; Yoshihiro Ohsima; Hajime Sakurai; Shingo Kasahara; Kisaburo Sakamoto
Journal:  Interact Cardiovasc Thorac Surg       Date:  2021-07-26

Review 3.  Current development of bovine jugular vein conduit for right ventricular outflow tract reconstruction.

Authors:  Chenggang Li; Bo Xie; Ruizhe Tan; Lijin Liang; Zhaoxiang Peng; Qi Chen
Journal:  Front Bioeng Biotechnol       Date:  2022-08-04

4.  Risk factors for early adverse outcomes after bovine jugular vein conduit implantation: influence of oversized conduit on the outcomes.

Authors:  Dong-Hee Kim; Young Kern Kwon; Eun Seok Choi; Bo Sang Kwon; Chun Soo Park; Tae-Jin Yun
Journal:  Interact Cardiovasc Thorac Surg       Date:  2022-09-09

5.  MRSA endocarditis of bovine Contegra valved conduit: a case report.

Authors:  Gani Bajraktari; Rozafa Olloni; Irfan Daullxhiu; Fadil Ademaj; Zana Vela; Mubekir Pajaziti
Journal:  Cases J       Date:  2009-01-15

Review 6.  Contegra conduit for reconstruction of the right ventricular outflow tract: a review of published early and mid-time results.

Authors:  Aristotle D Protopapas; Thanos Athanasiou
Journal:  J Cardiothorac Surg       Date:  2008-11-18       Impact factor: 1.637

7.  Pulmonary valve replacement after right ventricular outflow tract reconstruction with homograft vs Contegra®: a case control comparison of mortality and morbidity.

Authors:  Nicolas Poinot; Jean-Francois Fils; Hélène Demanet; Hugues Dessy; Dominique Biarent; Pierre Wauthy
Journal:  J Cardiothorac Surg       Date:  2018-01-17       Impact factor: 1.637

  7 in total

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