Literature DB >> 16934879

Antiviral activity of substituted homoisoflavonoids on enteroviruses.

Sabrina Tait1, Anna Laura Salvati, Nicoletta Desideri, Lucia Fiore.   

Abstract

The antiviral activity of homoisoflavonoids, a class of flavonoids, was determined in vitro against a large panel of enteroviruses. The inhibition of viral replication was monitored on BGM (Buffalo Green Monkey) cells, and the concentration required for 50% inhibition (IC50), as well as the selectivity index (SI) were determined. None of the substances were effective against Sabin type 1 poliovirus (PV1), but most of them showed a low cytotoxicity and a marked antiviral activity against Coxsackie virus B1, B3, B4, A9 and echovirus 30.

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Year:  2006        PMID： 16934879     DOI： 10.1016/j.antiviral.2006.07.003

Source DB:  PubMed          Journal:  Antiviral Res        ISSN： 0166-3542            Impact factor:   5.970


  16 in total

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Journal:  Futur J Pharm Sci       Date:  2021-06-15

9.  Synthesis and cytotoxic evaluation of some new[1,3]dioxolo[4,5-g]chromen-8-one derivatives.

Authors:  Eskandar Alipour; Zinatsadat Mousavi; Zahra Safaei; Mahboobeh Pordeli; Maliheh Safavi; Loghman Firoozpour; Negar Mohammadhosseini; Mina Saeedi; Sussan Kabudanian Ardestani; Abbas Shafiee; Alireza Foroumadi
Journal:  Daru       Date:  2014-05-02       Impact factor: 3.117

10.  Anti-poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real-time PCR.

Authors:  M C Búfalo; A S Figueiredo; J P B de Sousa; J M G Candeias; J K Bastos; J M Sforcin
Journal:  J Appl Microbiol       Date:  2009-04-21       Impact factor: 3.772
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