| Literature DB >> 16934456 |
Hong Nie1, Katherine L Widdowson, Michael R Palovich, Wei Fu, John D Elliott, Deborah L Bryan, Miriam Burman, Dulcie B Schmidt, James J Foley, Henry M Sarau, Jakob Busch-Petersen.
Abstract
A series of N-(2-hydroxy-3-sulfonamidobenzene)-N'-arylcyanoguanidines was prepared. In general, these compounds proved to be potent antagonists of CXCR2 while the selectivity versus CXCR1 ranged from non-selective to >200-fold.Entities:
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Year: 2006 PMID： 16934456 DOI： 10.1016/j.bmcl.2006.08.042
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823