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Literature DB >> 16934357

Genetic architecture of the dog: sexual size dimorphism and functional morphology.

Karl G Lark¹, Kevin Chase, Nathan B Sutter.

Abstract

Purebred dogs are a valuable resource for genetic analysis of quantitative traits. Quantitative traits are complex, controlled by many genes that are contained within regions of the genome known as quantitative trait loci (QTL). The genetic architecture of quantitative traits is defined by the characteristics of these genes: their number, the magnitude of their effects, their positions in the genome and their interactions with each other. QTL analysis is a valuable tool for exploring genetic architecture, and highlighting regions of the genome that contribute to the variation of a trait within a population.

Entities: Species

Mesh：

Year: 2006 PMID： 16934357 PMCID： PMC2785546 DOI： 10.1016/j.tig.2006.08.009

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

37 in total

Review 1. Microsatellite mutations in the germline: implications for evolutionary inference.

Authors: H Ellegren
Journal: Trends Genet Date: 2000-12 Impact factor: 11.639

Review 2. Mapping and analysis of quantitative trait loci in experimental populations.

Authors: Rebecca W Doerge
Journal: Nat Rev Genet Date: 2002-01 Impact factor: 53.242

Review 3. Understanding quantitative genetic variation.

Authors: N H Barton; P D Keightley
Journal: Nat Rev Genet Date: 2002-01 Impact factor: 53.242

Review 4. Unleashing the canine genome.

Authors: E A Ostrander; L Kruglyak
Journal: Genome Res Date: 2000-09 Impact factor: 9.043

5. Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components.

Authors: S C Pratt; M J Daly; L Kruglyak
Journal: Am J Hum Genet Date: 2000-03 Impact factor: 11.025

Review 6. Finding genes that underlie complex traits.

Authors: Anne M Glazier; Joseph H Nadeau; Timothy J Aitman
Journal: Science Date: 2002-12-20 Impact factor: 47.728

7. A 1-Mb resolution radiation hybrid map of the canine genome.

Authors: Richard Guyon; Travis D Lorentzen; Christophe Hitte; Lisa Kim; Edouard Cadieu; Heidi G Parker; Pascale Quignon; Jennifer K Lowe; Corinne Renier; Boris Gelfenbeyn; Françoise Vignaux; Hawkins B DeFrance; Stephanie Gloux; Gregory G Mahairas; Catherine André; Francis Galibert; Elaine A Ostrander
Journal: Proc Natl Acad Sci U S A Date: 2003-04-16 Impact factor: 11.205

8. Paternity success and the direction of sexual selection in a field population of a semelparous marsupial, Antechinus agilis.

Authors: F J L Kraaijeveld-Smit; S J Ward; P D Temple-Smith
Journal: Mol Ecol Date: 2003-02 Impact factor: 6.185

9. Genetic basis for systems of skeletal quantitative traits: principal component analysis of the canid skeleton.

Authors: Kevin Chase; David R Carrier; Frederick R Adler; Tyler Jarvik; Elaine A Ostrander; Travis D Lorentzen; Karl G Lark
Journal: Proc Natl Acad Sci U S A Date: 2002-07-11 Impact factor: 11.205

10. Bilaterally asymmetric effects of quantitative trait loci (QTLs): QTLs that affect laxity in the right versus left coxofemoral (hip) joints of the dog (Canis familiaris).

Authors: Kevin Chase; Dennis F Lawler; Fred R Adler; Elaine A Ostrander; Karl G Lark
Journal: Am J Med Genet A Date: 2004-01-30 Impact factor: 2.802

14 in total

1. Directional asymmetry in the limbs, skull and pelvis of the silver fox (V. vulpes).

Authors: Anastasia V Kharlamova; Lyudmila N Trut; Kevin Chase; Anna V Kukekova; Karl G Lark
Journal: J Morphol Date: 2010-12 Impact factor: 1.804

2. Age relationships of postmortem observations in Portuguese Water Dogs.

Authors: Kevin Chase; Dennis F Lawler; Lawrence D McGill; Shawn Miller; Mark Nielsen; Karl G Lark
Journal: Age (Dordr) Date: 2010-09-16

3. Genetic mapping of principal components of canine pelvic morphology.

Authors: Mark J Fealey; Joy Li; Rebel J E Todhunter; Ursula Krotscheck; Kei Hayashi; Marina J McConkey; Adam R Boyko; Jessica J Hayward; Rory J Todhunter
Journal: Canine Genet Epidemiol Date: 2017-03-24

4. Genetic regulation of canine skeletal traits: trade-offs between the hind limbs and forelimbs in the fox and dog.

Authors: Anastasia V Kharlamova; Lyudmila N Trut; David R Carrier; Kevin Chase; Karl G Lark
Journal: Integr Comp Biol Date: 2007-09 Impact factor: 3.326

5. A simple genetic architecture underlies morphological variation in dogs.

Authors: Adam R Boyko; Pascale Quignon; Lin Li; Jeffrey J Schoenebeck; Jeremiah D Degenhardt; Kirk E Lohmueller; Keyan Zhao; Abra Brisbin; Heidi G Parker; Bridgett M vonHoldt; Michele Cargill; Adam Auton; Andy Reynolds; Abdel G Elkahloun; Marta Castelhano; Dana S Mosher; Nathan B Sutter; Gary S Johnson; John Novembre; Melissa J Hubisz; Adam Siepel; Robert K Wayne; Carlos D Bustamante; Elaine A Ostrander
Journal: PLoS Biol Date: 2010-08-10 Impact factor: 8.029

6. A meiotic linkage map of the silver fox, aligned and compared to the canine genome.

Authors: Anna V Kukekova; Lyudmila N Trut; Irina N Oskina; Jennifer L Johnson; Svetlana V Temnykh; Anastasiya V Kharlamova; Darya V Shepeleva; Rimma G Gulievich; Svetlana G Shikhevich; Alexander S Graphodatsky; Gustavo D Aguirre; Gregory M Acland
Journal: Genome Res Date: 2007-02-06 Impact factor: 9.043

7. Fine mapping a locus controlling leg morphology in the domestic dog.

Authors: P Quignon; J J Schoenebeck; K Chase; H G Parker; D S Mosher; G S Johnson; K G Lark; E A Ostrander
Journal: Cold Spring Harb Symp Quant Biol Date: 2009-08-28

8. Single-nucleotide-polymorphism-based association mapping of dog stereotypes.

Authors: Paul Jones; Kevin Chase; Alan Martin; Pluis Davern; Elaine A Ostrander; Karl G Lark
Journal: Genetics Date: 2008-05-27 Impact factor: 4.562

Review 9. Development and use of DNA archives at veterinary teaching hospitals to investigate the genetic basis of disease in dogs.

Authors: Marta G P Castelhano; Gregory M Acland; Penelope A Ciccone; Elizabeth E Corey; Jason G Mezey; John C Schimenti; Rory J Todhunter
Journal: J Am Vet Med Assoc Date: 2009-01-01 Impact factor: 1.936

10. Differential genetic regulation of canine hip dysplasia and osteoarthritis.

Authors: Zhengkui Zhou; Xihui Sheng; Zhiwu Zhang; Keyan Zhao; Lan Zhu; Gang Guo; Steve G Friedenberg; Linda S Hunter; Wendy S Vandenberg-Foels; William E Hornbuckle; Ursula Krotscheck; Elizabeth Corey; Nancy S Moise; Nathan L Dykes; Junya Li; Shangzhong Xu; Lixin Du; Yachun Wang; Jody Sandler; Gregory M Acland; George Lust; Rory J Todhunter
Journal: PLoS One Date: 2010-10-11 Impact factor: 3.240