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Literature DB >> 16932750

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.

Abstract

The interferon-regulatory factor (IRF) family of transcription factors was initially found to be involved in the induction of genes that encode type I interferons. IRFs have now been shown to have functionally diverse roles in the regulation of the immune system. Recently, the crucial involvement of IRFs in innate and adaptive immune responses has been gaining much attention, particularly with the discovery of their role in immunoregulation by Toll-like receptors and other pattern-recognition receptors.

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Year: 2006 PMID： 16932750 DOI： 10.1038/nri1900

Source DB: PubMed Journal: Nat Rev Immunol ISSN： 1474-1733 Impact factor: 53.106

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Cited

649 in total

1. Extended safety and efficacy studies of the attenuated Brucella vaccine candidates 16 M(Delta)vjbR and S19(Delta)vjbR in the immunocompromised IRF-1-/- mouse model.

Authors: A M Arenas-Gamboa; A C Rice-Ficht; Y Fan; M M Kahl-McDonagh; T A Ficht
Journal: Clin Vaccine Immunol Date: 2011-12-14

2. IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.

Authors: Peyman Nakhaei; Qiang Sun; Mayra Solis; Thibault Mesplede; Eric Bonneil; Suzanne Paz; Rongtuan Lin; John Hiscott
Journal: J Virol Date: 2011-11-09 Impact factor: 5.103

3. Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility.

Authors: Anne-Pascale Satie; Severine Mazaud-Guittot; Isabelle Seif; Dominique Mahé; Zhiguo He; Guilhem Jouve; Bernard Jégou; Nathalie Dejucq-Rainsford
Journal: J Biol Chem Date: 2011-04-22 Impact factor: 5.157

Review 4. Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.

Authors: Kristina Ludigs; Valeriy Parfenov; Renaud A Du Pasquier; Greta Guarda
Journal: Cell Mol Life Sci Date: 2012-04-24 Impact factor: 9.261

5. Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.

Authors: Jeanette Erbo Christensen; Christina Fenger; Shohreh Issazadeh-Navikas; Anna Krug; Peter Liljestrøm; Stanislas Goriely; Søren Riis Paludan; Bente Finsen; Jan Pravsgaard Christensen; Allan Randrup Thomsen
Journal: J Virol Date: 2012-04-18 Impact factor: 5.103

6. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.

Authors: Qiming Liang; Hongying Deng; Xiaojuan Li; Xianfang Wu; Qiyi Tang; Tsung-Hsien Chang; Hongzhuang Peng; Frank J Rauscher; Keiko Ozato; Fanxiu Zhu
Journal: J Immunol Date: 2011-09-21 Impact factor: 5.422

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.

1. Extended safety and efficacy studies of the attenuated Brucella vaccine candidates 16 M(Delta)vjbR and S19(Delta)vjbR in the immunocompromised IRF-1-/- mouse model.

2. IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.

3. Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility.

Review 4. Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.

5. Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.

6. Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.

Review 7. Innate antiviral immune signaling, viral evasion and modulation by HIV-1.

8. The central adaptor molecule TRIF influences L. sigmodontis worm development.

Review 9. Innate and adaptive immune responses to Listeria monocytogenes: a short overview.

10. Interferon regulatory factor 6 regulates keratinocyte migration.