| Literature DB >> 16932578 |
Tim Harrower1, Tom Foltynie, Luke Kartsounis, Rajith N De Silva, John R Hodges.
Abstract
BACKGROUND: A 56-year-old man presented to hospital with a 6-month history of recurrent episodes of altered behavior and 'odd' episodes. He had become apathetic and uninterested in his family. He had no relevant past medical or family history. General and physical neurological examinations were unremarkable, as was bedside cognitive testing. INVESTIGATIONS: Brain MRI scan, 24-h electroencephalogram, serum and cerebrospinal fluid testing for voltage-gated potassium channel antibodies, blood screening for tumors, CT scans of the chest, abdomen and pelvis, whole-body PET scan, neuropsychological examination, brain 18F-fluorodeoxyglucose-PET scan. DIAGNOSIS: Voltage-gated potassium channel antibody-related limbic encephalitis. MANAGEMENT: Antiepileptic drugs, immunomodulatory therapy, oral steroids, plasma exchange.Entities:
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Year: 2006 PMID： 16932578 DOI： 10.1038/ncpneuro0194
Source DB: PubMed Journal: Nat Clin Pract Neurol ISSN： 1745-834X