| Literature DB >> 1693221 |
H von Briesen1, R Andreesen, R Esser, W Brugger, C Meichsner, K Becker, H Rübsamen-Waigmann.
Abstract
Because of the very important role of the mononuclear phagocyte system in the immunopathogenesis of HIV infection, a culture system for in vitro studies of infection of monocytes/macrophages with HIV was developed. A method is described for the infection of human monocytes/macrophages cultured on hydrophobic membranes (Teflon) with different strains of HIV. The HIV isolates can be characterized according to their replication potential on monocytes/macrophages cultures. The biological properties of some HIV1 and HIV2 isolates are compared in lymphocyte and monocyte/macrophage cultures.Entities:
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Year: 1990 PMID: 1693221 DOI: 10.1016/0923-2516(90)90025-e
Source DB: PubMed Journal: Res Virol ISSN: 0923-2516