Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Riboswitches: fold and function.

Literature DB >> 16931328

Riboswitches: fold and function.

Abstract

Riboswitches in the 5'-untranslated regions of mRNAs cotranscriptionally couple ligand binding and gene regulation. In this issue of Chemistry & Biology, Lemay et al. describe folding of a key tertiary interaction in the adenine riboswitch and its mechanistic consequences.

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 16931328 DOI： 10.1016/j.chembiol.2006.08.002

Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521

Keyword Cloud
Cited

15 in total

1. Thermodynamic and kinetic analysis of an RNA kissing interaction and its resolution into an extended duplex.

Authors: Nilshad Salim; Rajan Lamichhane; Rui Zhao; Tuhina Banerjee; Jane Philip; David Rueda; Andrew L Feig
Journal: Biophys J Date: 2012-03-06 Impact factor: 4.033

2. Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism.

Authors: Otmar M Ottink; Sumientra M Rampersad; Marco Tessari; Guido J R Zaman; Hans A Heus; Sybren S Wijmenga
Journal: RNA Date: 2007-10-24 Impact factor: 4.942

3. Screening for engineered neomycin riboswitches that control translation initiation.

Authors: Julia E Weigand; Martin Sanchez; Ewald-Bernd Gunnesch; Sabrina Zeiher; Renee Schroeder; Beatrix Suess
Journal: RNA Date: 2007-11-13 Impact factor: 4.942

4. Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches.

Authors: Purshotam Sharma; Sitansh Sharma; Mohit Chawla; Abhijit Mitra
Journal: J Mol Model Date: 2009-01-10 Impact factor: 1.810

5. MD simulations of ligand-bound and ligand-free aptamer: molecular level insights into the binding and switching mechanism of the add A-riboswitch.

Authors: Monika Sharma; Gopalakrishnan Bulusu; Abhijit Mitra
Journal: RNA Date: 2009-07-22 Impact factor: 4.942

Riboswitches: fold and function.

1. Thermodynamic and kinetic analysis of an RNA kissing interaction and its resolution into an extended duplex.

2. Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism.

3. Screening for engineered neomycin riboswitches that control translation initiation.

4. Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches.

5. MD simulations of ligand-bound and ligand-free aptamer: molecular level insights into the binding and switching mechanism of the add A-riboswitch.

6. Constitutive regulatory activity of an evolutionarily excluded riboswitch variant.

7. Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.

8. Role of the adenine ligand on the stabilization of the secondary and tertiary interactions in the adenine riboswitch.

9. Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping.

10. Mechanism of mRNA destabilization by the glmS ribozyme.