| Literature DB >> 16930367 |
F Fregni1, R Marcondes, P S Boggio, M A Marcolin, S P Rigonatti, T G Sanchez, M A Nitsche, A Pascual-Leone.
Abstract
Modulation of activity in the left temporoparietal area (LTA) by 10 Hz repetitive transcranial magnetic stimulation (rTMS) results in a transient reduction of tinnitus. We aimed to replicate these results and test whether transcranial direct current stimulation (tDCS) of LTA could yield similar effect. Patients with tinnitus underwent six different types of stimulation in a random order: 10-Hz rTMS of LTA, 10-Hz rTMS of mesial parietal cortex, sham rTMS, anodal tDCS of LTA, cathodal tDCS of LTA and sham tDCS. A non-parametric analysis of variance showed a significant main effect of type of stimulation (P = 0.002) and post hoc tests showed that 10-Hz rTMS and anodal tDCS of LTA resulted in a significant reduction of tinnitus. These effects were short lasting. These results replicate the findings of the previous study and, in addition, show preliminary evidence that anodal tDCS of LTA induces a similar transient tinnitus reduction as high-frequency rTMS.Entities:
Mesh：
Year: 2006 PMID： 16930367 DOI： 10.1111/j.1468-1331.2006.01414.x
Source DB: PubMed Journal: Eur J Neurol ISSN： 1351-5101 Impact factor: 6.089