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Literature DB >> 16928338

Rheumatoid arthritis and the heart.

Hilal Maradit Kremers¹, Sherine E Gabriel.

Abstract

The risk of cardiovascular disease is increased in patients with rheumatoid arthritis (RA). Although the pathogenesis of cardiovascular disease in patients with RA is largely unknown, evidence to date indicates that it involves complex interactions between the traditional and nontraditional cardiovascular risk factors as well as various medications commonly used for the treatment of RA patients. This review provides an overview of the clinical studies that demonstrate increased risk of coronary heart disease and heart failure in patients with RA and also discusses the potential role of the various risk factors.

Entities: Disease Species

Mesh：

Year: 2006 PMID： 16928338 DOI： 10.1007/s11897-006-0003-0

Source DB: PubMed Journal: Curr Heart Fail Rep ISSN： 1546-9530

42 in total

1. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

Authors: F E Silverstein; G Faich; J L Goldstein; L S Simon; T Pincus; A Whelton; R Makuch; G Eisen; N M Agrawal; W F Stenson; A M Burr; W W Zhao; J D Kent; J B Lefkowith; K M Verburg; G S Geis
Journal: JAMA Date: 2000-09-13 Impact factor: 56.272

2. Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis.

Authors: Robert Bergholm; Marjatta Leirisalo-Repo; Satu Vehkavaara; Sari Mäkimattila; Marja-Riitta Taskinen; Hannele Yki-Järvinen
Journal: Arterioscler Thromb Vasc Biol Date: 2002-10-01 Impact factor: 8.311

Review 3. Atherosclerosis in patients with autoimmune disorders.

Authors: Johan Frostegård
Journal: Arterioscler Thromb Vasc Biol Date: 2005-06-23 Impact factor: 8.311

4. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors.

Authors: I D del Rincón; K Williams; M P Stern; G L Freeman; A Escalante
Journal: Arthritis Rheum Date: 2001-12

1. Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages.

Authors: Allison B Reiss; Steven E Carsons; Kamran Anwar; Soumya Rao; Sari D Edelman; Hongwei Zhang; Patricia Fernandez; Bruce N Cronstein; Edwin S L Chan
Journal: Arthritis Rheum Date: 2008-12

1 in total

Rheumatoid arthritis and the heart.

1. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

2. Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis.

Review 3. Atherosclerosis in patients with autoimmune disorders.

4. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors.

5. Nonsteroidal antiinflammatory drugs as a trigger of clinical heart failure.

6. The risk of congestive heart failure in rheumatoid arthritis: a population-based study over 46 years.

7. Atherosclerosis in rheumatoid arthritis: morphologic evidence obtained by carotid ultrasound.

8. Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial.

Review 9. Inflammatory mediators and the failing heart: a translational approach.

10. Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis.

1. Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages.