Literature DB >> 16928043

Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction.

Koichi Mitsudo1, Praew Thansandote, Thorsten Wilhelm, Brian Mariampillai, Mark Lautens.   

Abstract

A variety of di- and trisubstituted thiophenes were synthesized by a one-pot palladium-catalyzed ortho-alkylation sequence terminated by either Heck or C-H coupling. Initial results toward the functionalization of indoles are also presented.

Entities:  

Year:  2006        PMID: 16928043     DOI: 10.1021/ol061373t

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Palladium/Norbornene Cooperative Catalysis.

Authors:  Jianchun Wang; Guangbin Dong
Journal:  Chem Rev       Date:  2019-04-25       Impact factor: 60.622

2.  Direct Vicinal Difunctionalization of Thiophenes Enabled by the Palladium/Norbornene Cooperative Catalysis.

Authors:  Renhe Li; Yun Zhou; Xiaolong Xu; Guangbin Dong
Journal:  J Am Chem Soc       Date:  2019-11-22       Impact factor: 15.419

3.  Multicomponent type II anion relay chemistry (ARC): one-pot syntheses of 2,3-disubstituted furans and thiophenes.

Authors:  Nelmi O Devarie-Baez; Won-Suk Kim; Amos B Smith; Ming Xian
Journal:  Org Lett       Date:  2009-04-16       Impact factor: 6.005

  3 in total

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