Literature DB >> 16926133

Leukemia stem cells.

Ling Luo1, Zhong Chao Han.   

Abstract

Cancer is a multifaceted disease in which cell proliferation is no longer under normal growth control. Accumulating data have suggested the existence of cancer stem cells, a minor population of tumor cells that possess the stem cell property of self-renewal and that are responsible for the initiation and maintenance of cancer. The knowledge of cancer stem cell biology is most advanced in research on the hematopoietic cancer, leukemia. With the identification of leukemia stem cells (LSCs) capable of repopulating nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, this body of research has led to conclusive proof for cancer stem cells. This review focuses on the biological characterization of LSCs for each type of leukemia, which has provided key insights into leukemogenic pathology and LSC-targeted therapies.

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Year:  2006        PMID： 16926133     DOI： 10.1532/IJH97.A10503

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  49 in total

Review 1.  Wnt signaling and cancer.

Authors:  P Polakis
Journal:  Genes Dev       Date:  2000-08-01       Impact factor: 11.361

2.  Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.

Authors:  Scott A Armstrong; Andrew L Kung; Meghann E Mabon; Lewis B Silverman; Ronald W Stam; Monique L Den Boer; Rob Pieters; John H Kersey; Stephen E Sallan; Jonathan A Fletcher; Todd R Golub; James D Griffin; Stanley J Korsmeyer
Journal:  Cancer Cell       Date:  2003-02       Impact factor: 31.743

Review 3.  The Hedgehog and Wnt signalling pathways in cancer.

Authors:  J Taipale; P A Beachy
Journal:  Nature       Date:  2001-05-17       Impact factor: 49.962

4.  Chronic myelogenous leukemia--identifying the hydra's heads.

Authors:  Michael F Clarke
Journal:  N Engl J Med       Date:  2004-08-12       Impact factor: 91.245

Review 5.  Concepts of human leukemic development.

Authors:  Jennifer K Warner; Jean C Y Wang; Kristin J Hope; Liqing Jin; John E Dick
Journal:  Oncogene       Date:  2004-09-20       Impact factor: 9.867

6.  Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.

Authors:  M Bhatia; J C Wang; U Kapp; D Bonnet; J E Dick
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-13       Impact factor: 11.205

Review 7.  Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia.

Authors:  T L Holyoake; X Jiang; M W Drummond; A C Eaves; C J Eaves
Journal:  Leukemia       Date:  2002-04       Impact factor: 11.528

8.  Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation.

Authors:  G Bhardwaj; B Murdoch; D Wu; D P Baker; K P Williams; K Chadwick; L E Ling; F N Karanu; M Bhatia
Journal:  Nat Immunol       Date:  2001-02       Impact factor: 25.606

Review 9.  Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

Authors:  Emmanuelle Passegué; Catriona H M Jamieson; Laurie E Ailles; Irving L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-22       Impact factor: 11.205

10.  The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: biologic significance and implications for the assessment of minimal residual disease.

Authors:  S Bose; M Deininger; J Gora-Tybor; J M Goldman; J V Melo
Journal:  Blood       Date:  1998-11-01       Impact factor: 22.113
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  5 in total

Review 1.  Can less really be more? Using lessons from leukemia and cancer stem cells to make sense of oral maintenance for metastatic sarcoma.

Authors:  Timothy P Cripe
Journal:  Pediatr Blood Cancer       Date:  2008-04       Impact factor: 3.167

Review 2.  Mutant DNA methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia initiation and relapse.

Authors:  Yuting Tan; Han Liu; Saijuan Chen
Journal:  Front Med       Date:  2015-12       Impact factor: 4.592

3.  Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression.

Authors:  Tetsuo Hirano; Ryoko Yoshikawa; Hironori Harada; Yuka Harada; Atsuhiko Ishida; Takeshi Yamazaki
Journal:  Mol Cancer       Date:  2015-04-19       Impact factor: 27.401

4.  Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus.

Authors:  Yonatan Y Mahller; Jon P Williams; William H Baird; Bryan Mitton; Jonathan Grossheim; Yoshinaga Saeki; Jose A Cancelas; Nancy Ratner; Timothy P Cripe
Journal:  PLoS One       Date:  2009-01-21       Impact factor: 3.240

5.  Survival outcomes of CD34+CD38-LSCs and their expression of CD123 in adult AML patients.

Authors:  Asmaa M Zahran; Sanaa Shaker Aly; Amal Rayan; Omnia El-Badawy; Maged Abdel Fattah; Arwa Mohammed Ali; Hala M ElBadre; Helal F Hetta
Journal:  Oncotarget       Date:  2018-09-25
  5 in total

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