Literature DB >> 1692580

Radiation sensitization by an iodine-labelled DNA ligand.

R F Martin1, V Murray, G D'Cunha, M Pardee, E Kampouris, A Haigh, D P Kelly, G S Hodgson.   

Abstract

An iodinated DNA ligand, iodo Hoechst 33258, which binds in the minor groove of DNA, enhances DNA strand breakage and cell killing by UV-A irradiation. The sites of UV-induced strand breaks reflect the known sequence specificity of the ligand.

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Year:  1990        PMID: 1692580     DOI: 10.1080/09553009014551061

Source DB:  PubMed          Journal:  Int J Radiat Biol        ISSN: 0955-3002            Impact factor:   2.694


  4 in total

1.  Ultraviolet light-induced cleavage of DNA in the presence of iodoHoechst 33258: the sequence specificity of the reaction.

Authors:  V Murray; R F Martin
Journal:  Nucleic Acids Res       Date:  1994-02-11       Impact factor: 16.971

2.  Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.

Authors:  C J Squire; L J Baker; G R Clark; R F Martin; J White
Journal:  Nucleic Acids Res       Date:  2000-03-01       Impact factor: 16.971

Review 3.  Transferrin receptor-mediated endocytosis: a useful target for cancer therapy.

Authors:  Stephanie Tortorella; Tom C Karagiannis
Journal:  J Membr Biol       Date:  2014-02-27       Impact factor: 1.843

4.  Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair.

Authors:  Barbara Steurer; Yasemin Turkyilmaz; Marvin van Toorn; Wessel van Leeuwen; Paula Escudero-Ferruz; Jurgen A Marteijn
Journal:  Nucleic Acids Res       Date:  2019-04-23       Impact factor: 16.971

  4 in total

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