Literature DB >> 16924654

Influence of initial component temperature on the apparent viscosity and handling characteristics of acrylic (PMMA) bone cement.

Stacey J Losaw Sullivan1, L D Timmie Topoleski.   

Abstract

The flow and polymerization characteristics of poly(methylmethacrylate) (PMMA) bone cement can be changed by manipulating the temperature of the bone cement components or the environment that they are prepared in. To quantify the effects of the initial component temperature (T(ic)) of acrylic bone cement on the rheological and handling characteristics, ASTM F451-99a compliant methods and clinically relevant testing methods were utilized. A rheometer was designed and fabricated using the dimensions of a clinical, commercially available, cement gun and nozzle. The influence on the apparent viscosity and handling characteristics (setting time, working time, and peak exotherm temperature) for a high viscosity (HV) commercially-available acrylic bone cement, Palacos R, were determined. The values of T(ic) used were 23 degrees C (room), 6 degrees C (refrigerator), and -14 degrees C (freezer). Using the apparent viscosity of a medium viscosity (MV) bone cement as a benchmark (Simplex P at room temperature), it was found that by adjusting the T(ic) the HV cement was able to mimic the flow characteristics of the MV cement. Lowering the T(ic) lowered the apparent viscosity of the bone cement. The effects of T(ic) on the polymerization of bone cement were studied in dynamic and static conditions. The dynamic test recorded temperature and torque from stirring resistance. Setting times were also determined using the ASTM exotherm mold method. The setting times determined by the dynamic testing conditions were consistently shorter than those determined by the ASTM method. Lowering the T(ic) increased the working and setting times; however, it did not have a significant effect on the peak exotherm temperature. (c) 2006 Wiley Periodicals, Inc.

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Year:  2007        PMID: 16924654     DOI: 10.1002/jbm.b.30657

Source DB:  PubMed          Journal:  J Biomed Mater Res B Appl Biomater        ISSN: 1552-4973            Impact factor:   3.368


  3 in total

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Authors:  Jyh-Horng Wang; Tai-Horng Young; Tzu-Hao Tseng; Chih-Hao Chang; Chien-Lin Chen; Hongsen Chiang; Hao-Ying Hsieh
Journal:  BMC Musculoskelet Disord       Date:  2022-10-14       Impact factor: 2.562

2.  Effect of storage temperature and equilibration time on polymethyl methacrylate (PMMA) bone cement polymerization in joint replacement surgery.

Authors:  Bryan T H Koh; J H Tan; Amit Kumarsing Ramruttun; Wilson Wang
Journal:  J Orthop Surg Res       Date:  2015-11-17       Impact factor: 2.359

3.  Experimental investigations of the aerated polymethylmethacrylate-based vertebral cement flow in capillaries.

Authors:  Zbigniew Tyfa; Dariusz Witkowski; Krzysztof Sobczak; Damian Obidowski; Krzysztof Jóźwik
Journal:  Int J Artif Organs       Date:  2018-07-18       Impact factor: 1.595

  3 in total

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