Literature DB >> 16924097

In search of an effective obesity treatment: a shot in the dark or a shot in the arm?

Jeffrey M Zigman1, Joel K Elmquist.   

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Year:  2006        PMID： 16924097      PMCID： PMC1559734          DOI： 10.1073/pnas.0605959103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  30 in total

Review 1.  Minireview: ghrelin and the regulation of energy balance--a hypothalamic perspective.

Authors:  T L Horvath; S Diano; P Sotonyi; M Heiman; M Tschöp
Journal:  Endocrinology       Date:  2001-10       Impact factor: 4.736

2.  Deletion of ghrelin impairs neither growth nor appetite.

Authors:  Yuxiang Sun; Saira Ahmed; Roy G Smith
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

3.  Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.

Authors:  A Asakawa; A Inui; T Kaga; H Yuzuriha; T Nagata; N Ueno; S Makino; M Fujimiya; A Niijima; M A Fujino; M Kasuga
Journal:  Gastroenterology       Date:  2001-02       Impact factor: 22.682

Review 4.  Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor.

Authors:  M Kojima; H Hosoda; H Matsuo; K Kangawa
Journal:  Trends Endocrinol Metab       Date:  2001-04       Impact factor: 12.015

5.  A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.

Authors:  D E Cummings; J Q Purnell; R S Frayo; K Schmidova; B E Wisse; D S Weigle
Journal:  Diabetes       Date:  2001-08       Impact factor: 9.461

6.  Ghrelin induces adiposity in rodents.

Authors:  M Tschöp; D L Smiley; M L Heiman
Journal:  Nature       Date:  2000-10-19       Impact factor: 49.962

7.  Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides.

Authors:  M Matsumoto; H Hosoda; Y Kitajima; N Morozumi; Y Minamitake; S Tanaka; H Matsuo; M Kojima; Y Hayashi; K Kangawa
Journal:  Biochem Biophys Res Commun       Date:  2001-09-14       Impact factor: 3.575

8.  Ghrelin causes hyperphagia and obesity in rats.

Authors:  A M Wren; C J Small; C R Abbott; W S Dhillo; L J Seal; M A Cohen; R L Batterham; S Taheri; S A Stanley; M A Ghatei; S R Bloom
Journal:  Diabetes       Date:  2001-11       Impact factor: 9.461

9.  Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.

Authors:  Yuxiang Sun; Pei Wang; Hui Zheng; Roy G Smith
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-18       Impact factor: 11.205

10.  Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.

Authors:  H Hosoda; M Kojima; H Matsuo; K Kangawa
Journal:  Biochem Biophys Res Commun       Date:  2000-12-29       Impact factor: 3.575
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  6 in total

1.  Intrarenal ghrelin receptor inhibition ameliorates angiotensin II-dependent hypertension in rats.

Authors:  Brandon A Kemp; Nancy L Howell; Shetal H Padia
Journal:  Am J Physiol Renal Physiol       Date:  2018-06-20

2.  Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides.

Authors:  Jing Yang; Tong-Jin Zhao; Joseph L Goldstein; Michael S Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-31       Impact factor: 11.205

3.  Interactions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists.

Authors:  Anna-Sophia Wisser; Piet Habbel; Bertram Wiedenmann; Burghard F Klapp; Hubert Mönnikes; Peter Kobelt
Journal:  Int J Pept       Date:  2010-01-06

4.  Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells.

Authors:  Ichiro Sakata; Jing Yang; Charlotte E Lee; Sherri Osborne-Lawrence; Sherry A Rovinsky; Joel K Elmquist; Jeffrey M Zigman
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-04-28       Impact factor: 4.310

5.  Characterization of a novel ghrelin cell reporter mouse.

Authors:  Ichiro Sakata; Yoshihide Nakano; Sherri Osborne-Lawrence; Sherry A Rovinsky; Charlotte E Lee; Mario Perello; Jason G Anderson; Roberto Coppari; Guanghua Xiao; Bradford B Lowell; Joel K Elmquist; Jeffrey M Zigman
Journal:  Regul Pept       Date:  2009-04-08

6.  Tackling obesity: new therapeutic agents for assisted weight loss.

Authors:  Jg Karam; Si McFarlane
Journal:  Diabetes Metab Syndr Obes       Date:  2010-04-26       Impact factor: 3.168
  6 in total

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