| Literature DB >> 16923385 |
Abstract
Limitations on a differentiated cell's pluripotency can be erased by nuclear transfer or by fusion with embryonic stem cells, but attempts to recapitulate this process of nuclear reprogramming by molecular means have failed. In this issue of Cell, Takahashi and Yamanaka (2006) take a rational approach to identifying a suite of embryonic transcription factors whose overexpression restores pluripotency to adult somatic cells.Mesh：
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Year: 2006 PMID： 16923385 DOI： 10.1016/j.cell.2006.08.009
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582