| Literature DB >> 16923382 |
Sharona Even-Ram1, Vira Artym, Kenneth M Yamada.
Abstract
A key challenge in stem cell research is to learn how to direct the differentiation of stem cells toward specific fates. In this issue of Cell, Engler et al. (2006) identify a new factor regulating stem cell fate: the elasticity of the matrix microenvironment. By changing the stiffness of the substrate, human mesenchymal stem cells could be directed along neuronal, muscle, or bone lineages.Entities:
Mesh:
Year: 2006 PMID: 16923382 DOI: 10.1016/j.cell.2006.08.008
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582