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Literature DB >> 1692167

The G protein-channel connection.

Abstract

Recent interest in the regulation of ion currents by hormones and neurotransmitters has focused on the role of G proteins as modulators. Which G proteins are involved? How is this regulation achieved? Initial results suggest that the pathways and mechanisms of action are complex and that delineation of this area of regulation has just begun.

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Year: 1990 PMID： 1692167 DOI： 10.1016/0166-2236(90)90002-r

Source DB: PubMed Journal: Trends Neurosci ISSN： 0166-2236 Impact factor: 13.837

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Cited

16 in total

1. Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.

Authors: Kerstin Wirkner; Joana Schweigel; Zoltan Gerevich; Heike Franke; Clemens Allgaier; Edward Leon Barsoumian; Henning Draheim; Peter Illes
Journal: Br J Pharmacol Date: 2003-12-08 Impact factor: 8.739

Review 8. Age-related changes in signal transduction. Implications for neuronal transmission and potential for drug intervention.

Authors: T Fülöp; I Seres
Journal: Drugs Aging Date: 1994-11 Impact factor: 3.923

9. Voltage- and time-dependent inhibition of neuronal calcium channels by a GTP-binding protein in a mammalian cell line.

Authors: H Kasai
Journal: J Physiol Date: 1992-03 Impact factor: 5.182

10. A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists.

Authors: P F Méry; A M Frace; H C Hartzell; R Fischmeister
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1993-08 Impact factor: 3.000

The G protein-channel connection.

1. Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.

2. Retinal rods and cones have distinct G protein beta and gamma subunits.

Review 3. Receptor-receptor interactions as an integrative mechanism in nerve cells.

Review 4. The role of G proteins in transmembrane signalling.

5. Pertussis-toxin-sensitive inhibition by (-) baclofen of Ca signals in bovine chromaffin cells.

6. Inhibition by adenosine A(2A) receptors of NMDA but not AMPA currents in rat neostriatal neurons.

7. Abundant Gs alpha mRNA in basket cells of the dentate gyrus in adult rat hippocampus.

Review 8. Age-related changes in signal transduction. Implications for neuronal transmission and potential for drug intervention.

9. Voltage- and time-dependent inhibition of neuronal calcium channels by a GTP-binding protein in a mammalian cell line.

10. A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists.