Literature DB >> 1692151

Direct action of human granulocyte colony-stimulating factor on mature human neutrophils: flow-cytometric analysis.

S Kondo1, S Okamura, N Ohhara, Y Niho.   

Abstract

The direct effects of human granulocyte colony-stimulating factor (G-CSF) on mature neutrophils in vitro were studied using flow cytometry. G-CSF increased the neutrophil forward scatter without recruitment of side scatter, as assessed by flow cytometry. This indicates that G-CSF acts on neutrophils directly and induces the activation of mature neutrophils without degranulation of primary granules.

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Year:  1990        PMID: 1692151

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  2 in total

1.  Identification of a functional receptor for granulocyte colony-stimulating factor on platelets.

Authors:  K Shimoda; S Okamura; N Harada; S Kondo; T Okamura; Y Niho
Journal:  J Clin Invest       Date:  1993-04       Impact factor: 14.808

2.  Granulocyte colony-stimulating factor does not enhance phagocytosis or microbicidal activity of human mature polymorphonuclear neutrophils in vitro.

Authors:  N Shimono; K Okada; D Takeda; K Eguchi; H Misumi; Y Sawae; Y Niho
Journal:  Clin Diagn Lab Immunol       Date:  1994-09
  2 in total

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